Levels of house-dust-mite allergen in homes of non-allergic people in Pavia, Italy

Gianna Moscato, L. Perfetti, E. Galdi, V. Pozzi, C. Minoia

Research output: Contribution to journalArticle

Abstract

Background: HDM distribution varies between geographic areas and may be affected by housing characteristics. We quantified Der p 1 and Der f 1 and assessed the relationships between their levels and housing characteristics in homes of nonallergic subjects. Methods: Der f 1 and Der p 1 were measured by ELISA in dust samples from living-room floors and mattresses of 44 homes of nonallergic subjects in Pavia. Information about household characteristics was obtained by questionnaire. Results: Der p 1 and Der f 1 concentrations (μg/g dust, median) were 0.34 and 7.8 on mattresses, and 0.15 and 0.83 on living-room floors. Higher Der f 1 levels on mattresses were associated with synthetic pillows (P <0.05), and (only when expressed as μg/m2) with bedding washing temperature of ≤ 60°C (P <0.05). Der f 1 levels were higher on the living-room floors of homes located on lower (≤ first) floors (P <0.05). Good correlations were found between Der p 1 and Der f 1 expressed as μg/g dust and μg/m2 on both mattresses and living-room floors. Conclusions: In homes of nonallergic subjects in northern Italy, Der f 1 exceeded the threshold for sensitization in a high proportion of mattress samples.

Original languageEnglish
Pages (from-to)873-878
Number of pages6
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume55
Issue number9
DOIs
Publication statusPublished - 2000

Fingerprint

Dermatophagoides Antigens
Italy
Dust
Dermatophagoides farinae antigen f 1
Enzyme-Linked Immunosorbent Assay
Temperature
Dermatophagoides pteronyssinus antigen p 1

Keywords

  • Der f 1
  • Der p 1
  • Dermatophagoides farinae
  • Dermatophagoides pteronyssinus
  • Environment
  • House-dust mite
  • Household characteristics
  • Pillow
  • Risk factors

ASJC Scopus subject areas

  • Immunology

Cite this

Levels of house-dust-mite allergen in homes of non-allergic people in Pavia, Italy. / Moscato, Gianna; Perfetti, L.; Galdi, E.; Pozzi, V.; Minoia, C.

In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 55, No. 9, 2000, p. 873-878.

Research output: Contribution to journalArticle

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AU - Minoia, C.

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