Abstract
In patients with different types of solid tumors who had no detectable metastasis and had received no radio- and chemotherapy the levels of Ia-like antigen bearing lymphocytes was determined by indirect immunofluorescence staining of peripheral lymphocytes with xenoantisera to framework determinants of Ia-like antigens. The level of Ia-like antigen bearing lymphocytes was increased in patients with urinary bladder carcinoma, was decreased in patients with carcinoma of the gastro-intestinal tract and was within normal ranges in patients with melanoma, carcinomas of the breast, lung and genital tract. In patients with carcinomas of the gastrointestinal tract as well as in patients with carcinoma of lung and genital tract the level of T lymphocytes measured by rosetting with sheep red blood cells, was reduced while it was not different from normal in other groups of patients. Determination of the level of lymphocyte subpopulations may provide information about the immunocompetence status of patients with solid tumors.
| Original language | English |
|---|---|
| Pages (from-to) | 197-199 |
| Number of pages | 3 |
| Journal | Journal of Clinical and Laboratory Immunology |
| Volume | 6 |
| Issue number | 3 |
| Publication status | Published - 1981 |
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ASJC Scopus subject areas
- Immunology
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Levels of Ia-like antigen bearing lymphocytes in patients with solid primary tumors. / Cordiali-Fei, P.; Natali, P. G.; Pecci, G.; Pellegrino, M. A.; Ferrone, S.
In: Journal of Clinical and Laboratory Immunology, Vol. 6, No. 3, 1981, p. 197-199.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Levels of Ia-like antigen bearing lymphocytes in patients with solid primary tumors
AU - Cordiali-Fei, P.
AU - Natali, P. G.
AU - Pecci, G.
AU - Pellegrino, M. A.
AU - Ferrone, S.
PY - 1981
Y1 - 1981
N2 - In patients with different types of solid tumors who had no detectable metastasis and had received no radio- and chemotherapy the levels of Ia-like antigen bearing lymphocytes was determined by indirect immunofluorescence staining of peripheral lymphocytes with xenoantisera to framework determinants of Ia-like antigens. The level of Ia-like antigen bearing lymphocytes was increased in patients with urinary bladder carcinoma, was decreased in patients with carcinoma of the gastro-intestinal tract and was within normal ranges in patients with melanoma, carcinomas of the breast, lung and genital tract. In patients with carcinomas of the gastrointestinal tract as well as in patients with carcinoma of lung and genital tract the level of T lymphocytes measured by rosetting with sheep red blood cells, was reduced while it was not different from normal in other groups of patients. Determination of the level of lymphocyte subpopulations may provide information about the immunocompetence status of patients with solid tumors.
AB - In patients with different types of solid tumors who had no detectable metastasis and had received no radio- and chemotherapy the levels of Ia-like antigen bearing lymphocytes was determined by indirect immunofluorescence staining of peripheral lymphocytes with xenoantisera to framework determinants of Ia-like antigens. The level of Ia-like antigen bearing lymphocytes was increased in patients with urinary bladder carcinoma, was decreased in patients with carcinoma of the gastro-intestinal tract and was within normal ranges in patients with melanoma, carcinomas of the breast, lung and genital tract. In patients with carcinomas of the gastrointestinal tract as well as in patients with carcinoma of lung and genital tract the level of T lymphocytes measured by rosetting with sheep red blood cells, was reduced while it was not different from normal in other groups of patients. Determination of the level of lymphocyte subpopulations may provide information about the immunocompetence status of patients with solid tumors.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019847323&partnerID=8YFLogxK
M3 - Article
C2 - 6951050
AN - SCOPUS:0019847323
VL - 6
SP - 197
EP - 199
JO - Journal of Clinical and Laboratory Immunology
JF - Journal of Clinical and Laboratory Immunology
SN - 0141-2760
IS - 3
ER -