TY - JOUR
T1 - Levodopa may affect cortical excitability in Parkinson's disease patients with cognitive deficits as revealed by reduced activity of cortical sources of resting state electroencephalographic rhythms
AU - Babiloni, Claudio
AU - Del Percio, Claudio
AU - Lizio, Roberta
AU - Noce, Giuseppe
AU - Lopez, Susanna
AU - Soricelli, Andrea
AU - Ferri, Raffaele
AU - Pascarelli, Maria Teresa
AU - Catania, Valentina
AU - Nobili, Flavio
AU - Arnaldi, Dario
AU - Famà, Francesco
AU - Orzi, Francesco
AU - Buttinelli, Carla
AU - Giubilei, Franco
AU - Bonanni, Laura
AU - Franciotti, Raffaella
AU - Onofrj, Marco
AU - Stirpe, Paola
AU - Fuhr, Peter
AU - Gschwandtner, Ute
AU - Ransmayr, Gerhard
AU - Fraioli, Lucia
AU - Parnetti, Lucilla
AU - Farotti, Lucia
AU - Pievani, Michela
AU - D'Antonio, Fabrizia
AU - De Lena, Carlo
AU - Güntekin, Bahar
AU - Hanoğlu, Lutfu
AU - Yener, Görsev
AU - Emek-Savaş, Derya Durusu
AU - Triggiani, Antonio Ivano
AU - Taylor, John Paul
AU - McKeith, Ian
AU - Stocchi, Fabrizio
AU - Vacca, Laura
AU - Frisoni, Giovanni B
AU - De Pandis, Maria Francesca
N1 - Copyright © 2018 Elsevier Inc. All rights reserved.
PY - 2018/8/30
Y1 - 2018/8/30
N2 - We hypothesized that dopamine neuromodulation might affect cortical excitability in Parkinson's disease (PD) patients set in quiet wakefulness, as revealed by resting state eyes-closed electroencephalographic (rsEEG) rhythms at alpha frequencies (8-12 Hz). Clinical and rsEEG rhythms in PD with dementia (N = 35), PD with mild cognitive impairment (N = 50), PD with normal cognition (N = 35), and normal (N = 50) older adults were available from an international archive. Cortical rsEEG sources were estimated by exact low-resolution brain electromagnetic tomography. Compared with the normal older group, the PD groups showed reduced occipital alpha sources and increased widespread delta (
AB - We hypothesized that dopamine neuromodulation might affect cortical excitability in Parkinson's disease (PD) patients set in quiet wakefulness, as revealed by resting state eyes-closed electroencephalographic (rsEEG) rhythms at alpha frequencies (8-12 Hz). Clinical and rsEEG rhythms in PD with dementia (N = 35), PD with mild cognitive impairment (N = 50), PD with normal cognition (N = 35), and normal (N = 50) older adults were available from an international archive. Cortical rsEEG sources were estimated by exact low-resolution brain electromagnetic tomography. Compared with the normal older group, the PD groups showed reduced occipital alpha sources and increased widespread delta (
U2 - 10.1016/j.neurobiolaging.2018.08.010
DO - 10.1016/j.neurobiolaging.2018.08.010
M3 - Article
VL - 73
SP - 9
EP - 20
JO - Neurobiol. Aging
JF - Neurobiol. Aging
SN - 0197-4580
ER -