Lhermitte-duclos disease: A case report

Andrea Giorgianni, Carlo Pellegrino, Alessandro De Benedictis, Anna Mercuri, Fabio Baruzzi, Renzo Minotto, Antonio Tabano, Sergio Balbi

Research output: Contribution to journalArticle

Abstract

Lhermitte-Duclos disease is a rare pathologic condition consisting of a dysplastic gangliocytoma of the cerebellum. Its association with phacomatosis and an autosomal dominant neoplastic syndrome, Cowden's syndrome is also known. Modern neuroimaging contributes to a correct diagnosis and pre- and postoperative evaluation. Here we describe the morphologic and metabolic aspects of the disease as shown by conventional MRI, diffusion imaging and spectroscopy in a 31-year-old woman. In addition, the specific neuroradiologic characteristics are presented and discussed in the light of the main pathologic and clinical features, such as hypertrophy of the cerebellar folia associated with white matter atrophy.

Original languageEnglish
Pages (from-to)655-660
Number of pages6
JournalNeuroradiology Journal
Volume26
Issue number6
Publication statusPublished - Dec 2013

Keywords

  • Brain tumor
  • CT and MR imaging
  • Lhermitte-Duclos disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Giorgianni, A., Pellegrino, C., De Benedictis, A., Mercuri, A., Baruzzi, F., Minotto, R., Tabano, A., & Balbi, S. (2013). Lhermitte-duclos disease: A case report. Neuroradiology Journal, 26(6), 655-660.