Lichen planus and chronic active hepatitis. A retrospective survey

A. Rebora, F. Rongioletti

Research output: Contribution to journalArticle

Abstract

In a retrospective survey 95 in-patients with non erosive lichen planus (LP) were summoned to be investigated by means of routine liver tests. 44 patients responded. Remarkable abnormalities of liver tests were found in 6 patients who were further studied for antibodies to smooth muscle and mitochondria and submitted to liver biopsy. Histological diagnosis revealed chronic active hepatitis (CAH) in 5 cases (11.3%). Such an impressive prevalence and the histologic and immunologic similarities between the two diseases support the view that the association LP-CAH is not fortuitous and that both diseases may have the same autoimmune pathogenesis. Accordingly LP may be regarded as a major risk factor for liver cirrhosis.

Original languageEnglish
Pages (from-to)52-56
Number of pages5
JournalActa Dermato-Venereologica
Volume64
Issue number1
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Dermatology

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