Lichen sclerosus of the male genitalia and urethral stricture diseases

Guido Barbagli, Enzo Palminteri, Sofia Balò, Santiago Vallasciani, Ettore Mearini, Elisabetta Constantini, Luigi Mearini, Alessandro Zucchi, Carlo Vivacqua, Massimo Porena

Research output: Contribution to journalArticlepeer-review


Introduction: The true incidence of urethral involvement in patients with genital lichen sclerosus (LS) is unknown. We review the epidemiology and discuss the pathogenesis of LS and urethral stricture diseases. Materials and Methods: During the period 1991-2002, of 925 patients who underwent urethroplasty for anterior urethral stricture, 130 patients (14 %) received the diagnosis of LS. In all patients with LS the histology was re-examined to confi rm the clinical diagnosis. Retrograde and voiding urethrography was used to establish urethral involvement in the disease. Results: In 106 patients (82 %) the histology provided the classical features of LS, and 24 patients (18 %) showed some histological variations. In 49 patients (37 %) the LS involved the pendolous urethra (meatus-navicularis-penile), and in 53 cases (41 %) a panurethral stricture was evident. Conclusions: LS urethral involvement appears to be a much more common and extensive disease than previously reported, and requires particular care in its early diagnosis.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalUrologia Internationalis
Issue number1
Publication statusPublished - 2004

ASJC Scopus subject areas

  • Urology


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