Abstract
A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.
| Original language | English |
|---|---|
| Pages (from-to) | 963-964 |
| Number of pages | 2 |
| Journal | Journal of Pediatric Hematology/Oncology |
| Volume | 31 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2009 |
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Keywords
- Adrenal mass
- Cystic neuroblastoma
- Hepatic metastases
- Neonatal abdominal mass
- Neonatal surgery
- Spontaneous regression
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Oncology
- Hematology
- Medicine(all)
Cite this
Life-threatening bilateral adrenal cystic neuroblastoma in an infant. / Avanzini, Stefano; Conte, Massimo; Granata, Claudio; Zamorani, Enrica M.; Sementa, Angela R.; Garaventa, Alberto; Buffa, Piero; Sorrentino, Stefania.
In: Journal of Pediatric Hematology/Oncology, Vol. 31, No. 12, 12.2009, p. 963-964.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Life-threatening bilateral adrenal cystic neuroblastoma in an infant
AU - Avanzini, Stefano
AU - Conte, Massimo
AU - Granata, Claudio
AU - Zamorani, Enrica M.
AU - Sementa, Angela R.
AU - Garaventa, Alberto
AU - Buffa, Piero
AU - Sorrentino, Stefania
PY - 2009/12
Y1 - 2009/12
N2 - A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.
AB - A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.
KW - Adrenal mass
KW - Cystic neuroblastoma
KW - Hepatic metastases
KW - Neonatal abdominal mass
KW - Neonatal surgery
KW - Spontaneous regression
UR - http://www.scopus.com/inward/record.url?scp=73949123360&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=73949123360&partnerID=8YFLogxK
U2 - 10.1097/MPH.0b013e3181b79641
DO - 10.1097/MPH.0b013e3181b79641
M3 - Article
C2 - 19887960
AN - SCOPUS:73949123360
VL - 31
SP - 963
EP - 964
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
SN - 1077-4114
IS - 12
ER -