Life-threatening bilateral adrenal cystic neuroblastoma in an infant

Stefano Avanzini, Massimo Conte, Claudio Granata, Enrica M. Zamorani, Angela R. Sementa, Alberto Garaventa, Piero Buffa, Stefania Sorrentino

Research output: Contribution to journalArticlepeer-review


A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.

Original languageEnglish
Pages (from-to)963-964
Number of pages2
JournalJournal of Pediatric Hematology/Oncology
Issue number12
Publication statusPublished - Dec 2009


  • Adrenal mass
  • Cystic neuroblastoma
  • Hepatic metastases
  • Neonatal abdominal mass
  • Neonatal surgery
  • Spontaneous regression

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology
  • Medicine(all)


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