Life-threatening bilateral adrenal cystic neuroblastoma in an infant

Stefano Avanzini; Massimo Conte; Claudio Granata; Enrica M. Zamorani; Angela R. Sementa; Alberto Garaventa; Piero Buffa; Stefania Sorrentino

doi:10.1097/MPH.0b013e3181b79641

Life-threatening bilateral adrenal cystic neuroblastoma in an infant

Stefano Avanzini, Massimo Conte, Claudio Granata, Enrica M. Zamorani, Angela R. Sementa, Alberto Garaventa, Piero Buffa, Stefania Sorrentino

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.

Original language	English
Pages (from-to)	963-964
Number of pages	2
Journal	Journal of Pediatric Hematology/Oncology
Volume	31
Issue number	12
DOIs	https://doi.org/10.1097/MPH.0b013e3181b79641
Publication status	Published - Dec 2009

Keywords

Adrenal mass
Cystic neuroblastoma
Hepatic metastases
Neonatal abdominal mass
Neonatal surgery
Spontaneous regression

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Oncology
Hematology
Medicine(all)

Access to Document

10.1097/MPH.0b013e3181b79641

Cite this

Life-threatening bilateral adrenal cystic neuroblastoma in an infant. / Avanzini, Stefano ; Conte, Massimo ; Granata, Claudio; Zamorani, Enrica M.; Sementa, Angela R.; Garaventa, Alberto; Buffa, Piero; Sorrentino, Stefania.

In: Journal of Pediatric Hematology/Oncology, Vol. 31, No. 12, 12.2009, p. 963-964.

Research output: Contribution to journal › Article › peer-review

@article{337ab1db99a1408da4498dd47bf2c5fb,

title = "Life-threatening bilateral adrenal cystic neuroblastoma in an infant",

abstract = "A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.",

keywords = "Adrenal mass, Cystic neuroblastoma, Hepatic metastases, Neonatal abdominal mass, Neonatal surgery, Spontaneous regression",

author = "Stefano Avanzini and Massimo Conte and Claudio Granata and Zamorani, {Enrica M.} and Sementa, {Angela R.} and Alberto Garaventa and Piero Buffa and Stefania Sorrentino",

year = "2009",

month = dec,

doi = "10.1097/MPH.0b013e3181b79641",

language = "English",

volume = "31",

pages = "963--964",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams and Wilkins",

number = "12",

}

TY - JOUR

T1 - Life-threatening bilateral adrenal cystic neuroblastoma in an infant

AU - Avanzini, Stefano

AU - Conte, Massimo

AU - Granata, Claudio

AU - Zamorani, Enrica M.

AU - Sementa, Angela R.

AU - Garaventa, Alberto

AU - Buffa, Piero

AU - Sorrentino, Stefania

PY - 2009/12

Y1 - 2009/12

N2 - A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.

AB - A case of neonatal bilateral adrenal mass causing severe respiratory distress and requiring an emergency debulking surgical procedure is reported. Histopathology revealed a cystic neuroblastoma stroma poor, poorly differentiated, without MYCN amplification and 1p deletion. During postoperative follow-up, a progression to stage 4s was observed, characterized by liver involvement. According to good prognostic indexes, no further treatment was administered. Both adrenal masses and hepatic nodules showed progressive decrease in size, till complete disappearance. The authors encourage a multidisciplinary approach to develop the best patient-related strategy for cystic neuroblastoma, thus reducing complications rate.

KW - Adrenal mass

KW - Cystic neuroblastoma

KW - Hepatic metastases

KW - Neonatal abdominal mass

KW - Neonatal surgery

KW - Spontaneous regression

UR - http://www.scopus.com/inward/record.url?scp=73949123360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73949123360&partnerID=8YFLogxK

U2 - 10.1097/MPH.0b013e3181b79641

DO - 10.1097/MPH.0b013e3181b79641

M3 - Article

C2 - 19887960

AN - SCOPUS:73949123360

VL - 31

SP - 963

EP - 964

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

IS - 12

ER -

Life-threatening bilateral adrenal cystic neuroblastoma in an infant

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this