Lifestyle, nutrition and breast cancer: Facts and presumptions for consideration

Krizia Ferrini, Francesca Ghelfi, Roberta Mannucci, Lucilla Titta

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Breast cancer is the most common cancer in women worldwide, and the high incidence of this cancer coupled with improvements in initial treatments has led to an ever-increasing number of breast cancer survivors. Among the prospective epidemiological studies on diet and breast cancer incidence and recurrence, to date, there is no association that is strong, reproducible and statistically significant, with the exception of alcohol intake, overweight, and weight gain. Nevertheless, many beliefs about food and breast cancer persist in the absence of supporting scientific evidence. After a comprehensive review regarding the role of lifestyle on breast cancer outcomes and a thorough study of the dissemination field including mass media, clinical institutions, and academic figures, we briefly reported the most common presumptions and also facts from the literature regarding lifestyle, nutrition, and breast cancer. The randomised controlled trial is the best study-design that could provide direct evidence of a causal relationship; however, there are methodological difficulties in applying and maintaining a lifestyle intervention for a sufficient period; consequently, there is a lack of this type of study in the literature. Instead, it is possible to obtain indirect evidence from observational prospective studies. In this article, it becomes clear that for now the best advice for women's health is to follow the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) recommendations on diet, nutrition, physical activity, and weight management for cancer prevention, because they are associated with a lower risk of developing most types of cancer, including breast cancer. Despite current awareness of the role of nutrition in cancer outcomes, there is inadequate translation from research findings into clinical practice. We suggest the establishment of a multidisciplinary research consortium to demonstrate the real power of lifestyle interventions.

Original languageEnglish
Article number557
Journalecancermedicalscience
Volume9
DOIs
Publication statusPublished - Jul 23 2015

Fingerprint

Life Style
Breast Neoplasms
Neoplasms
Research
Prospective Studies
Diet
Mass Media
Incidence
Women's Health
Weight Gain
Observational Studies
Survivors
Epidemiologic Studies
Randomized Controlled Trials
Alcohols
Exercise
Weights and Measures
Recurrence
Food

Keywords

  • Body weight
  • Breast cancer
  • Cancer prevention
  • Lifestyle
  • Nutrition

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Lifestyle, nutrition and breast cancer : Facts and presumptions for consideration. / Ferrini, Krizia; Ghelfi, Francesca; Mannucci, Roberta; Titta, Lucilla.

In: ecancermedicalscience, Vol. 9, 557, 23.07.2015.

Research output: Contribution to journalArticle

@article{9477bd5b1f69417da55a2ee991dc8b61,
title = "Lifestyle, nutrition and breast cancer: Facts and presumptions for consideration",
abstract = "Breast cancer is the most common cancer in women worldwide, and the high incidence of this cancer coupled with improvements in initial treatments has led to an ever-increasing number of breast cancer survivors. Among the prospective epidemiological studies on diet and breast cancer incidence and recurrence, to date, there is no association that is strong, reproducible and statistically significant, with the exception of alcohol intake, overweight, and weight gain. Nevertheless, many beliefs about food and breast cancer persist in the absence of supporting scientific evidence. After a comprehensive review regarding the role of lifestyle on breast cancer outcomes and a thorough study of the dissemination field including mass media, clinical institutions, and academic figures, we briefly reported the most common presumptions and also facts from the literature regarding lifestyle, nutrition, and breast cancer. The randomised controlled trial is the best study-design that could provide direct evidence of a causal relationship; however, there are methodological difficulties in applying and maintaining a lifestyle intervention for a sufficient period; consequently, there is a lack of this type of study in the literature. Instead, it is possible to obtain indirect evidence from observational prospective studies. In this article, it becomes clear that for now the best advice for women's health is to follow the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) recommendations on diet, nutrition, physical activity, and weight management for cancer prevention, because they are associated with a lower risk of developing most types of cancer, including breast cancer. Despite current awareness of the role of nutrition in cancer outcomes, there is inadequate translation from research findings into clinical practice. We suggest the establishment of a multidisciplinary research consortium to demonstrate the real power of lifestyle interventions.",
keywords = "Body weight, Breast cancer, Cancer prevention, Lifestyle, Nutrition",
author = "Krizia Ferrini and Francesca Ghelfi and Roberta Mannucci and Lucilla Titta",
year = "2015",
month = "7",
day = "23",
doi = "10.3332/ecancer.2015.557",
language = "English",
volume = "9",
journal = "ecancermedicalscience",
issn = "1754-6605",
publisher = "Cancer Intellilgence",

}

TY - JOUR

T1 - Lifestyle, nutrition and breast cancer

T2 - Facts and presumptions for consideration

AU - Ferrini, Krizia

AU - Ghelfi, Francesca

AU - Mannucci, Roberta

AU - Titta, Lucilla

PY - 2015/7/23

Y1 - 2015/7/23

N2 - Breast cancer is the most common cancer in women worldwide, and the high incidence of this cancer coupled with improvements in initial treatments has led to an ever-increasing number of breast cancer survivors. Among the prospective epidemiological studies on diet and breast cancer incidence and recurrence, to date, there is no association that is strong, reproducible and statistically significant, with the exception of alcohol intake, overweight, and weight gain. Nevertheless, many beliefs about food and breast cancer persist in the absence of supporting scientific evidence. After a comprehensive review regarding the role of lifestyle on breast cancer outcomes and a thorough study of the dissemination field including mass media, clinical institutions, and academic figures, we briefly reported the most common presumptions and also facts from the literature regarding lifestyle, nutrition, and breast cancer. The randomised controlled trial is the best study-design that could provide direct evidence of a causal relationship; however, there are methodological difficulties in applying and maintaining a lifestyle intervention for a sufficient period; consequently, there is a lack of this type of study in the literature. Instead, it is possible to obtain indirect evidence from observational prospective studies. In this article, it becomes clear that for now the best advice for women's health is to follow the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) recommendations on diet, nutrition, physical activity, and weight management for cancer prevention, because they are associated with a lower risk of developing most types of cancer, including breast cancer. Despite current awareness of the role of nutrition in cancer outcomes, there is inadequate translation from research findings into clinical practice. We suggest the establishment of a multidisciplinary research consortium to demonstrate the real power of lifestyle interventions.

AB - Breast cancer is the most common cancer in women worldwide, and the high incidence of this cancer coupled with improvements in initial treatments has led to an ever-increasing number of breast cancer survivors. Among the prospective epidemiological studies on diet and breast cancer incidence and recurrence, to date, there is no association that is strong, reproducible and statistically significant, with the exception of alcohol intake, overweight, and weight gain. Nevertheless, many beliefs about food and breast cancer persist in the absence of supporting scientific evidence. After a comprehensive review regarding the role of lifestyle on breast cancer outcomes and a thorough study of the dissemination field including mass media, clinical institutions, and academic figures, we briefly reported the most common presumptions and also facts from the literature regarding lifestyle, nutrition, and breast cancer. The randomised controlled trial is the best study-design that could provide direct evidence of a causal relationship; however, there are methodological difficulties in applying and maintaining a lifestyle intervention for a sufficient period; consequently, there is a lack of this type of study in the literature. Instead, it is possible to obtain indirect evidence from observational prospective studies. In this article, it becomes clear that for now the best advice for women's health is to follow the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) recommendations on diet, nutrition, physical activity, and weight management for cancer prevention, because they are associated with a lower risk of developing most types of cancer, including breast cancer. Despite current awareness of the role of nutrition in cancer outcomes, there is inadequate translation from research findings into clinical practice. We suggest the establishment of a multidisciplinary research consortium to demonstrate the real power of lifestyle interventions.

KW - Body weight

KW - Breast cancer

KW - Cancer prevention

KW - Lifestyle

KW - Nutrition

UR - http://www.scopus.com/inward/record.url?scp=84938699593&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938699593&partnerID=8YFLogxK

U2 - 10.3332/ecancer.2015.557

DO - 10.3332/ecancer.2015.557

M3 - Article

AN - SCOPUS:84938699593

VL - 9

JO - ecancermedicalscience

JF - ecancermedicalscience

SN - 1754-6605

M1 - 557

ER -