Light chain deposition disease neuropathy resembling amyloid neuropathy in a multiple myeloma patient

M. P. Grassi, F. Clerici, C. Perin, M. Borella, A. Gendarini, A. Quattrini, R. Nemni, A. Mangoni

Research output: Contribution to journalArticlepeer-review

Abstract

A 65-year-old man with IgG lambda multiple myeloma developed severe polyneuropathy with prominent thermal-pain sensory impairment and autonomic failure. Although the clinical presentation suggested amyloid neuropathy, nerve biopsy showed the immunohistochemical and ultrastructural features typical of light chain deposition disease (LCDD). A precise morphologic and clinical description of LCDD neuropathy is given for the first time in the present report.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalItalian Journal of Neurological Sciences
Volume19
Issue number4
Publication statusPublished - 1998

Keywords

  • Amyloidosis
  • Light chain deposition disease
  • Multiple myeloma
  • Neuropathy

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology

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