Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus

Michele Abate, Cosima Schiavone, Patrizia Pelotti, Vincenzo Salini

Research output: Contribution to journalArticle

Abstract

LJM is frequently observed in young subjects with insulin-dependent diabetes mellitus (IDDM). Aim of this study was to evaluate whether non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of LJM in elderly subjects. Thirty patients (15 males, 15 females, mean age 73.93 ± 12.72 years) with NIDDM in good glycemic control were compared with thirty non-diabetic elderly, well matched for sex and age (15 males, 15 females, mean age 74.3 ± 4.24 years), and with ten young normal subjects (5 males, 5 females, mean age 26.3 ± 1.56 years). In these subjects, the range of motion (ROM) of ankle, knee, hip, elbow and shoulder were measured with a double-armed goniometer. Moreover, abnormalities of supraspinatus, patellar and Achilles tendons were evaluated with a standardized ultrasound (US) procedure. A significant reduction in the mobility of all joints was found in elderly subjects, compared to younger ones, with exception for the knee and elbow flexion. Elderly patients with diabetes, compared with their age-matched counterpart, showed LJM for ankle dorso- and plantar flexion, hip flexion and adduction, shoulder abduction and flexion. Moreover, tendons sonographic abnormalities were more frequently observed in diabetics. Our data confirm that diabetes worsens the LJM in the elderly, increasing the cross-linking of collagen by the non-enzymatic advanced glycation end products formation.

Original languageEnglish
Pages (from-to)135-140
Number of pages6
JournalArchives of Gerontology and Geriatrics
Volume53
Issue number2
DOIs
Publication statusPublished - Sep 2011

Fingerprint

Type 2 Diabetes Mellitus
chronic illness
Joints
Elbow
Hip
Knee
Patellar Ligament
abduction
Advanced Glycosylation End Products
Achilles Tendon
Rotator Cuff
Ankle Joint
Articular Range of Motion
Type 1 Diabetes Mellitus
Ankle
Tendons
Collagen

Keywords

  • Aging of diabetics
  • Diabetes
  • Joint mobility
  • Tendons in diabetic elderly
  • Ultrasonographic evaluation of joint mobility

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology
  • Health(social science)
  • Gerontology

Cite this

Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus. / Abate, Michele; Schiavone, Cosima; Pelotti, Patrizia; Salini, Vincenzo.

In: Archives of Gerontology and Geriatrics, Vol. 53, No. 2, 09.2011, p. 135-140.

Research output: Contribution to journalArticle

Abate, Michele ; Schiavone, Cosima ; Pelotti, Patrizia ; Salini, Vincenzo. / Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus. In: Archives of Gerontology and Geriatrics. 2011 ; Vol. 53, No. 2. pp. 135-140.
@article{ecddeea5ee844e28bdb4e8ec51b35f91,
title = "Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus",
abstract = "LJM is frequently observed in young subjects with insulin-dependent diabetes mellitus (IDDM). Aim of this study was to evaluate whether non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of LJM in elderly subjects. Thirty patients (15 males, 15 females, mean age 73.93 ± 12.72 years) with NIDDM in good glycemic control were compared with thirty non-diabetic elderly, well matched for sex and age (15 males, 15 females, mean age 74.3 ± 4.24 years), and with ten young normal subjects (5 males, 5 females, mean age 26.3 ± 1.56 years). In these subjects, the range of motion (ROM) of ankle, knee, hip, elbow and shoulder were measured with a double-armed goniometer. Moreover, abnormalities of supraspinatus, patellar and Achilles tendons were evaluated with a standardized ultrasound (US) procedure. A significant reduction in the mobility of all joints was found in elderly subjects, compared to younger ones, with exception for the knee and elbow flexion. Elderly patients with diabetes, compared with their age-matched counterpart, showed LJM for ankle dorso- and plantar flexion, hip flexion and adduction, shoulder abduction and flexion. Moreover, tendons sonographic abnormalities were more frequently observed in diabetics. Our data confirm that diabetes worsens the LJM in the elderly, increasing the cross-linking of collagen by the non-enzymatic advanced glycation end products formation.",
keywords = "Aging of diabetics, Diabetes, Joint mobility, Tendons in diabetic elderly, Ultrasonographic evaluation of joint mobility",
author = "Michele Abate and Cosima Schiavone and Patrizia Pelotti and Vincenzo Salini",
year = "2011",
month = "9",
doi = "10.1016/j.archger.2010.09.011",
language = "English",
volume = "53",
pages = "135--140",
journal = "Archives of Gerontology and Geriatrics",
issn = "0167-4943",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus

AU - Abate, Michele

AU - Schiavone, Cosima

AU - Pelotti, Patrizia

AU - Salini, Vincenzo

PY - 2011/9

Y1 - 2011/9

N2 - LJM is frequently observed in young subjects with insulin-dependent diabetes mellitus (IDDM). Aim of this study was to evaluate whether non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of LJM in elderly subjects. Thirty patients (15 males, 15 females, mean age 73.93 ± 12.72 years) with NIDDM in good glycemic control were compared with thirty non-diabetic elderly, well matched for sex and age (15 males, 15 females, mean age 74.3 ± 4.24 years), and with ten young normal subjects (5 males, 5 females, mean age 26.3 ± 1.56 years). In these subjects, the range of motion (ROM) of ankle, knee, hip, elbow and shoulder were measured with a double-armed goniometer. Moreover, abnormalities of supraspinatus, patellar and Achilles tendons were evaluated with a standardized ultrasound (US) procedure. A significant reduction in the mobility of all joints was found in elderly subjects, compared to younger ones, with exception for the knee and elbow flexion. Elderly patients with diabetes, compared with their age-matched counterpart, showed LJM for ankle dorso- and plantar flexion, hip flexion and adduction, shoulder abduction and flexion. Moreover, tendons sonographic abnormalities were more frequently observed in diabetics. Our data confirm that diabetes worsens the LJM in the elderly, increasing the cross-linking of collagen by the non-enzymatic advanced glycation end products formation.

AB - LJM is frequently observed in young subjects with insulin-dependent diabetes mellitus (IDDM). Aim of this study was to evaluate whether non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of LJM in elderly subjects. Thirty patients (15 males, 15 females, mean age 73.93 ± 12.72 years) with NIDDM in good glycemic control were compared with thirty non-diabetic elderly, well matched for sex and age (15 males, 15 females, mean age 74.3 ± 4.24 years), and with ten young normal subjects (5 males, 5 females, mean age 26.3 ± 1.56 years). In these subjects, the range of motion (ROM) of ankle, knee, hip, elbow and shoulder were measured with a double-armed goniometer. Moreover, abnormalities of supraspinatus, patellar and Achilles tendons were evaluated with a standardized ultrasound (US) procedure. A significant reduction in the mobility of all joints was found in elderly subjects, compared to younger ones, with exception for the knee and elbow flexion. Elderly patients with diabetes, compared with their age-matched counterpart, showed LJM for ankle dorso- and plantar flexion, hip flexion and adduction, shoulder abduction and flexion. Moreover, tendons sonographic abnormalities were more frequently observed in diabetics. Our data confirm that diabetes worsens the LJM in the elderly, increasing the cross-linking of collagen by the non-enzymatic advanced glycation end products formation.

KW - Aging of diabetics

KW - Diabetes

KW - Joint mobility

KW - Tendons in diabetic elderly

KW - Ultrasonographic evaluation of joint mobility

UR - http://www.scopus.com/inward/record.url?scp=79960103186&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960103186&partnerID=8YFLogxK

U2 - 10.1016/j.archger.2010.09.011

DO - 10.1016/j.archger.2010.09.011

M3 - Article

C2 - 20940076

AN - SCOPUS:79960103186

VL - 53

SP - 135

EP - 140

JO - Archives of Gerontology and Geriatrics

JF - Archives of Gerontology and Geriatrics

SN - 0167-4943

IS - 2

ER -