Linear and nonlinear dynamics of heart rate variability after acute myocardial infarction with normal and reduced left ventricular ejection fraction

Federico Lombardi, Giulia Sandrone, Andrea Mortara, Daniela Torzillo, Maria Teresa La Rovere, Maria Gabriella Signorini, Sergio Cerutti, Alberto Malliani

Research output: Contribution to journalArticle

112 Citations (Scopus)

Abstract

We analyzed heart rate variability (HRV) in 2 groups of patients after acute myocardial infarction with normal and reduced ejection fraction (EF) by considering both the power of the 2 major harmonic components at low and high frequency and 2 indexes of nonlinear dynamics, namely the 1/f slope and the correlation dimension D2. HRV of patients with a reduced EF was characterized by a diminished RR variance as well as a different distribution of the residual power in all frequency ranges, with lower values of the low- frequency component expressed in both absolute and normalized units, and of the low- to high-frequency ratio. In these patients we also observed a steeper slope of the negative regression line between power and frequency in the very low frequency range. The presence of a smaller fractal dimension was suggested by a lower D2. Thus, in patients after acute myocardial infarction with a reduced EF, the reduction in HRV is associated with a different distribution of the residual power in the entire frequency range, which suggests a diminished responsiveness of sinus node to neural modulatory inputs.

Original languageEnglish
Pages (from-to)1283-1288
Number of pages6
JournalThe American Journal of Cardiology
Volume77
Issue number15
DOIs
Publication statusPublished - Jun 15 1996

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Nonlinear Dynamics
Stroke Volume
Heart Rate
Myocardial Infarction
Fractals
Sinoatrial Node

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Linear and nonlinear dynamics of heart rate variability after acute myocardial infarction with normal and reduced left ventricular ejection fraction. / Lombardi, Federico; Sandrone, Giulia; Mortara, Andrea; Torzillo, Daniela; La Rovere, Maria Teresa; Signorini, Maria Gabriella; Cerutti, Sergio; Malliani, Alberto.

In: The American Journal of Cardiology, Vol. 77, No. 15, 15.06.1996, p. 1283-1288.

Research output: Contribution to journalArticle

Lombardi, Federico ; Sandrone, Giulia ; Mortara, Andrea ; Torzillo, Daniela ; La Rovere, Maria Teresa ; Signorini, Maria Gabriella ; Cerutti, Sergio ; Malliani, Alberto. / Linear and nonlinear dynamics of heart rate variability after acute myocardial infarction with normal and reduced left ventricular ejection fraction. In: The American Journal of Cardiology. 1996 ; Vol. 77, No. 15. pp. 1283-1288.
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AU - Signorini, Maria Gabriella

AU - Cerutti, Sergio

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