Linear discriminant functions to improve the glaucoma probability score analysis to detect glaucomatous optic nerve heads: A multicenter study

Michele Iester; Francesco Oddone; Mirko Prato; Marco Centofanti; Paolo Fogagnolo; Luca Rossetti; Valeria Vaccarezza; Gianluca Manni; Antonio Ferreras

doi:10.1097/IJG.0b013e31823298b3

Linear discriminant functions to improve the glaucoma probability score analysis to detect glaucomatous optic nerve heads: A multicenter study

Michele Iester, Francesco Oddone, Mirko Prato, Marco Centofanti, Paolo Fogagnolo, Luca Rossetti, Valeria Vaccarezza, Gianluca Manni, Antonio Ferreras

Fondazione G.B. Bietti

Research output: Contribution to journal › Article

Abstract

Purpose: The purpose of the study was to create a linear discriminant function (LDF) formula by using the new Glaucoma Probability Score (GPS) global and sectorial optic nerve head parameters measured by Heidelberg Retinal Tomograph 3 to improve the GPS diagnostic capacity to discriminate between healthy and glaucomatous eyes. Patients and Methods: This is a multicenter cross-sectional study. To calculate the LDF formula, 137 normal individuals and 96 glaucomatous patients were selected. Another independent sample of 60 healthy and 69 glaucomatous eyes was used to evaluate the diagnostic accuracy of the LDF formulas. All patients underwent a full eye examination, standard achromatic perimetry by using Humphrey Field Analyzer, and imaging with Heidelberg Retinal Tomograph 3. Glaucoma was defined on the basis of SITA-24-2 visual field loss (pattern standard deviation P

Original language	English
Pages (from-to)	73-79
Number of pages	7
Journal	Journal of Glaucoma
Volume	22
Issue number	2
DOIs	https://doi.org/10.1097/IJG.0b013e31823298b3
Publication status	Published - Feb 2013

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Keywords

Confocal scanning laser
Disc area
Discriminant analysis formula
Glaucoma
Heidelberg Retina Tomography
Stage

ASJC Scopus subject areas

Ophthalmology

Cite this

Iester, M., Oddone, F., Prato, M., Centofanti, M., Fogagnolo, P., Rossetti, L., Vaccarezza, V., Manni, G., & Ferreras, A. (2013). Linear discriminant functions to improve the glaucoma probability score analysis to detect glaucomatous optic nerve heads: A multicenter study. Journal of Glaucoma, 22(2), 73-79. https://doi.org/10.1097/IJG.0b013e31823298b3

Linear discriminant functions to improve the glaucoma probability score analysis to detect glaucomatous optic nerve heads : A multicenter study. / Iester, Michele; Oddone, Francesco; Prato, Mirko; Centofanti, Marco; Fogagnolo, Paolo; Rossetti, Luca; Vaccarezza, Valeria; Manni, Gianluca; Ferreras, Antonio.

In: Journal of Glaucoma, Vol. 22, No. 2, 02.2013, p. 73-79.

Research output: Contribution to journal › Article

Iester, Michele ; Oddone, Francesco ; Prato, Mirko ; Centofanti, Marco ; Fogagnolo, Paolo ; Rossetti, Luca ; Vaccarezza, Valeria ; Manni, Gianluca ; Ferreras, Antonio. / Linear discriminant functions to improve the glaucoma probability score analysis to detect glaucomatous optic nerve heads : A multicenter study. In: Journal of Glaucoma. 2013 ; Vol. 22, No. 2. pp. 73-79.

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Access to Document

10.1097/IJG.0b013e31823298b3