Linear lupus erythematosus profundus in an adolescent

Daniele Innocenzi, Guglielho Pranteda, Stephano Giombini, Vitaliano Silipo, Ugo Bottoni, Stephano Calvieri

Research output: Contribution to journalArticlepeer-review


A 17-year-old Italian boy presented a 3-year history of violaceous, macular lesions of the breast and internal surface of the right arm with a characteristic linear distribution. A biopsy specimen revealed a lymphohistiocytic panniculitis, and periappendageal and perivascular infiltrates of lymphocytes occasionally involving the blood vessel walls in the deep dermis and hypodermis. Focal hydropic degeneration of basal cells was also evident. Direct immunofluorescence revealed linear focal deposits of IgM at the dermoepidermal junction. Antinuclear antibodies were positive. Histopathology, direct immunofluorescence and immunological assays allowed us to diagnose lupus erythematosus profundus. To our knowledge, only one other case of linear lupus erythematosus profundus has been reported in the literature until now.

Original languageEnglish
Pages (from-to)445-447
Number of pages3
JournalEuropean Journal of Dermatology
Issue number6
Publication statusPublished - 1997


  • Linear lupus
  • Lupus erythematosus profundus
  • Lupus panniculitis

ASJC Scopus subject areas

  • Dermatology


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