Linguistic development in a patient with Landau-Kleffner syndrome: A nine-year follow-up

G. Zardini, B. Molteni, N. Nardocci, D. Sarti, G. Avanzini, T. Granata

Research output: Contribution to journalArticlepeer-review


A longitudinal linguistic analysis of aphasic disorder in a 15-year-old boy affected by Landau-Kleffner syndrome followed since the age of 6 is reported. The phonological, morphosyntactic and lexical levels of verbal deficits have been evaluated by means of collected samples of spontaneous language and a battery of linguistic tests. The clinical course has fluctuated with improvement and worsening of aphasia and epilepsy; at the end of the follow-up the boy was seizure-free and a medium-degree disturbance in language production and comprehension was present. The results of the linguistic evaluation suggest that the aphasic disturbance was related to a deficiency in phonological decoding which leads to phonological, morphosyntactic and lexical disturbances. A temporal relationship between the electroclinical picture and the aphasia has been observed: the persistent improvement in linguistic performances took place only after the disappearance of the seizures and of the EEG epileptic anomalies during sleep.

Original languageEnglish
Pages (from-to)19-25
Number of pages7
Issue number1
Publication statusPublished - 1995


  • Acquired aphasia
  • Landau-Kleffner syndrome
  • Linguistic assessment
  • Phonological decoding

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health


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