Abstract
A patient self-rated 19-item wearing-off questionnaire (WOQ-19) was shown to be a potent screening tool for wearing-off (WO) in patients with Parkinson's disease. As part of the early detection of wearing-off in Parkinson's disease study, we preliminarily performed a linguistic and a psychometric validation of an Italian version of the WOQ-19. Moreover, we assessed the sensitivity and specificity of the WOQ-19 in the office-based settings. The psychometric validation study included assessment of discriminant ability, internal consistency and test-retest reliability. The intraclass correlation coefficient (ICC) and the Cronbach's Alpha were assessed. The WOQ-19 sensitivity and specificity were calculated in respect to the physician assessment of WO, taken as the gold standard. The Italian version of WOQ-19 was found easy to understand by ≥80% of the patients. The number of WO-related symptoms detected by WOQ-19 was 7.5 ± 3.2 in patients with WO and 1.6 ± 2.6 in patients without WO (p
| Original language | English |
|---|---|
| Pages (from-to) | 1319-1327 |
| Number of pages | 9 |
| Journal | Neurological Sciences |
| Volume | 33 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Mar 23 2012 |
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Keywords
- Motor fluctuations
- Non-motor fluctuations
- Parkinson's disease
- Wearing-off
- Wearing-off patient questionnaire
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Dermatology
- Medicine(all)
Cite this
Linguistic, psychometric validation and diagnostic ability assessment of an Italian version of a 19-item wearing-off questionnaire for wearing-off detection in Parkinson's disease. / Abbruzzese, Giovanni; Antonini, Angelo; Barone, Paolo; Stocchi, Fabrizio; Tamburini, Tiziano; Bernardi, Laura; Amboni, Marianna; Vacca, Laura; Posocco, Valeria; Colombo, Delia.
In: Neurological Sciences, Vol. 33, No. 6, 23.03.2012, p. 1319-1327.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Linguistic, psychometric validation and diagnostic ability assessment of an Italian version of a 19-item wearing-off questionnaire for wearing-off detection in Parkinson's disease
AU - Abbruzzese, Giovanni
AU - Antonini, Angelo
AU - Barone, Paolo
AU - Stocchi, Fabrizio
AU - Tamburini, Tiziano
AU - Bernardi, Laura
AU - Amboni, Marianna
AU - Vacca, Laura
AU - Posocco, Valeria
AU - Colombo, Delia
PY - 2012/3/23
Y1 - 2012/3/23
N2 - A patient self-rated 19-item wearing-off questionnaire (WOQ-19) was shown to be a potent screening tool for wearing-off (WO) in patients with Parkinson's disease. As part of the early detection of wearing-off in Parkinson's disease study, we preliminarily performed a linguistic and a psychometric validation of an Italian version of the WOQ-19. Moreover, we assessed the sensitivity and specificity of the WOQ-19 in the office-based settings. The psychometric validation study included assessment of discriminant ability, internal consistency and test-retest reliability. The intraclass correlation coefficient (ICC) and the Cronbach's Alpha were assessed. The WOQ-19 sensitivity and specificity were calculated in respect to the physician assessment of WO, taken as the gold standard. The Italian version of WOQ-19 was found easy to understand by ≥80% of the patients. The number of WO-related symptoms detected by WOQ-19 was 7.5 ± 3.2 in patients with WO and 1.6 ± 2.6 in patients without WO (p
AB - A patient self-rated 19-item wearing-off questionnaire (WOQ-19) was shown to be a potent screening tool for wearing-off (WO) in patients with Parkinson's disease. As part of the early detection of wearing-off in Parkinson's disease study, we preliminarily performed a linguistic and a psychometric validation of an Italian version of the WOQ-19. Moreover, we assessed the sensitivity and specificity of the WOQ-19 in the office-based settings. The psychometric validation study included assessment of discriminant ability, internal consistency and test-retest reliability. The intraclass correlation coefficient (ICC) and the Cronbach's Alpha were assessed. The WOQ-19 sensitivity and specificity were calculated in respect to the physician assessment of WO, taken as the gold standard. The Italian version of WOQ-19 was found easy to understand by ≥80% of the patients. The number of WO-related symptoms detected by WOQ-19 was 7.5 ± 3.2 in patients with WO and 1.6 ± 2.6 in patients without WO (p
KW - Motor fluctuations
KW - Non-motor fluctuations
KW - Parkinson's disease
KW - Wearing-off
KW - Wearing-off patient questionnaire
UR - http://www.scopus.com/inward/record.url?scp=84883509247&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883509247&partnerID=8YFLogxK
U2 - 10.1007/s10072-012-0943-y
DO - 10.1007/s10072-012-0943-y
M3 - Article
VL - 33
SP - 1319
EP - 1327
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 6
ER -