Linkage and sequence conservation of the X-linked genes DXS253E (P3) and DXS254E (GdX) in mouse and man

Mercedes Filippi, Carla Tribioli, Daniela Toniolo

Research output: Contribution to journalArticle

Abstract

Lambda G28, a mouse genomic clone homologous to the human P3 gene and associated with a CpG island, also hybridizes to human probes for the neighboring GdX gene. The two genes, P3 and GdX (DXS253E and DXS254E), physically linked on the human X chromosome, lie within a similar physical distance on the mouse X chromosome. The CpG island corresponds to that at the 5′ of the human GdX gene. The relative orientation of the two genes is the same. The DNA sequence in coding and noncoding regions is very conserved.

Original languageEnglish
Pages (from-to)453-457
Number of pages5
JournalGenomics
Volume7
Issue number3
DOIs
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Genetics

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