Linkage relationships between retinoschisis, Xg, and a cloned DNA sequence from the distal short arm of the X chromosome

P. Wieacker, T. F. Wienker, B. Dallapiccola, K. Bender, Kay E. Davies, H. H. Ropers

Research output: Contribution to journalArticlepeer-review

Abstract

A cloned DNA sequence, RC8, from the short arm of the X chromosome which is linked to the Duchenne muscular dystrophy (DMD) gene has been employed to study linkage relationships with the Xg-linked retinoschisis (RS) locus. Results of three point linkage analyses in two families suggest that the gene order on Xp is Xg-RS-RC8. Moreover, it can be inferred from these data that the genetic distance between Xg and DMD is approximately 55 cM.

Original languageEnglish
Pages (from-to)143-145
Number of pages3
JournalHuman Genetics
Volume64
Issue number2
DOIs
Publication statusPublished - Aug 1983

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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