Lipids on the move

Phosphoinositide 3-kinases in leukocyte function

Matthias P. Wymann, Silvano Sozzani, Fiorella Altruda, Alberto Mantovani, Emilio Hirsch

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

All four known cell surface receptor-activated phosphoinositide 3-kinases have been found in leukocytes. Matthias Wymann and colleagues discuss their nonredundant roles in leukocyte function, particularly in chemotaxis, and their promise as targets for therapeutic intervention.

Original languageEnglish
Pages (from-to)260-264
Number of pages5
JournalImmunology Today
Volume21
Issue number6
DOIs
Publication statusPublished - Jun 1 2000

Fingerprint

1-Phosphatidylinositol 4-Kinase
Leukocytes
Lipids
Cell Surface Receptors
Chemotaxis
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

Lipids on the move : Phosphoinositide 3-kinases in leukocyte function. / Wymann, Matthias P.; Sozzani, Silvano; Altruda, Fiorella; Mantovani, Alberto; Hirsch, Emilio.

In: Immunology Today, Vol. 21, No. 6, 01.06.2000, p. 260-264.

Research output: Contribution to journalArticle

Wymann, Matthias P. ; Sozzani, Silvano ; Altruda, Fiorella ; Mantovani, Alberto ; Hirsch, Emilio. / Lipids on the move : Phosphoinositide 3-kinases in leukocyte function. In: Immunology Today. 2000 ; Vol. 21, No. 6. pp. 260-264.
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