Lipoprotein(a), fibrinogen and vascular mortality in an elderly northern Italian population

Armando D'Angelo, Giacomo Ruotolo, Paola Garancini, Francesca Sampietro, Giuseppina Mazzola, Giliola Calori

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background and Objectives. High lipoprotein a [Lp(a)] and fibrinogen levels are suggested risk factors for coronary heart disease (CHD) and stroke morbidity and mortality. Experimental data strongly suggest that the mechanisms of atherothrombosis include an interaction between fibrinogen and Lp(a), but little clinical evidence of a synergism between these two parameters has been reported. Design and Methods. Within the frame of a prospective population study conducted in the area of Cremona (Lombardy, Italy), 343 women and 216 men aged ≥65 years were evaluated for clinical and biochemical cardiovascular risk factors. Lp(a) levels ≥30 mg/dL were observed in 22.7% and 23.9% of men and women, respectively. Fibrinogen levels were higher in women (p

Original languageEnglish
Pages (from-to)1613-1620
Number of pages8
JournalHaematologica
Volume91
Issue number12
Publication statusPublished - Dec 2006

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Lipoprotein(a)
Fibrinogen
Blood Vessels
Mortality
Population
Italy
Coronary Disease
Stroke
Prospective Studies
Morbidity

Keywords

  • C-reactive protein
  • Coronary heart disease
  • Fibrinogen
  • Insulin
  • Lp(a)
  • Stroke

ASJC Scopus subject areas

  • Hematology

Cite this

D'Angelo, A., Ruotolo, G., Garancini, P., Sampietro, F., Mazzola, G., & Calori, G. (2006). Lipoprotein(a), fibrinogen and vascular mortality in an elderly northern Italian population. Haematologica, 91(12), 1613-1620.

Lipoprotein(a), fibrinogen and vascular mortality in an elderly northern Italian population. / D'Angelo, Armando; Ruotolo, Giacomo; Garancini, Paola; Sampietro, Francesca; Mazzola, Giuseppina; Calori, Giliola.

In: Haematologica, Vol. 91, No. 12, 12.2006, p. 1613-1620.

Research output: Contribution to journalArticle

D'Angelo, A, Ruotolo, G, Garancini, P, Sampietro, F, Mazzola, G & Calori, G 2006, 'Lipoprotein(a), fibrinogen and vascular mortality in an elderly northern Italian population', Haematologica, vol. 91, no. 12, pp. 1613-1620.
D'Angelo, Armando ; Ruotolo, Giacomo ; Garancini, Paola ; Sampietro, Francesca ; Mazzola, Giuseppina ; Calori, Giliola. / Lipoprotein(a), fibrinogen and vascular mortality in an elderly northern Italian population. In: Haematologica. 2006 ; Vol. 91, No. 12. pp. 1613-1620.
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