Liposoluble vitamins and lipid parameters in breast cancer. A joint study in northern Italy and southern France

M. Gerber, F. Cavallo, E. Marubini, S. Richardson, A. Barbieri, E. Capitelli, A. Costa, A. Crastes de Paulet, P. Crastes de Paulet, A. Decarli, U. Pastorino, H. Pujol

Research output: Contribution to journalArticle

Abstract

The relationship between breast cancer, liposoluble vitamins, cholesterol and triglycerides was investigated by means of a hospital-based case-control study conducted at Milan (Italy) and Montpellier (France). These parameters were measured in blood samples taken from 319 cases and 344 controls. The interview included an evaluation of dietary intake of liposoluble vitamins. No difference emerged in liposoluble vitamin consumption, whereas a statistically significantly higher serum level of cholesterol and plasma level of vitamin E existed in cases compared to controls. The difference in plasma vitamin E was confirmed after adjustment for total cholesterol to follow triglyceride trends. A multivariate analysis of the vitamin E plasma level was performed after classification of cases and controls according to quintile distribution of controls. All known risk factors plus age, serum total cholesterol and triglycerides were used as covariates. The odds ratio value for the highest quintile of plasma vitamin E is: 4.2 (1.9-9.0).

Original languageEnglish
Pages (from-to)489-494
Number of pages6
JournalInternational Journal of Cancer
Volume42
Issue number4
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Gerber, M., Cavallo, F., Marubini, E., Richardson, S., Barbieri, A., Capitelli, E., Costa, A., Crastes de Paulet, A., Crastes de Paulet, P., Decarli, A., Pastorino, U., & Pujol, H. (1988). Liposoluble vitamins and lipid parameters in breast cancer. A joint study in northern Italy and southern France. International Journal of Cancer, 42(4), 489-494.