Lipoxygenase and apoptosis in microgravity

M. Maccarrone, N. Battista, M. Bari, A. Finazzi Agrò

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Recently, attention is drawn to the role of lipoxygenase (LOX) in the execution of mammalian cell apoptosis, a process which seems to play a critical role also in cell sensitivity to Space conditions. By introducing oxygen into the fatty acid moieties of (phospho)lipids, LOXs can alter fluidity and permeability of biomembranes. Such modifications at the membrane level may play a regulatory role in the physiological clearance mechanism of apoptotic cells.

Original languageEnglish
Title of host publicationEuropean Space Agency, (Special Publication) ESA SP
Number of pages4
Publication statusPublished - Sep 2002
EventProceedings of the European Symposium on Life in Space for Life on Earth - Stockholm, Sweden
Duration: Jun 2 2002Jun 7 2002


OtherProceedings of the European Symposium on Life in Space for Life on Earth

ASJC Scopus subject areas

  • Aerospace Engineering


Dive into the research topics of 'Lipoxygenase and apoptosis in microgravity'. Together they form a unique fingerprint.

Cite this