Lipoxygenase and apoptosis in microgravity

M. Maccarrone, N. Battista, M. Bari, A. Finazzi Agrò

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently, attention is drawn to the role of lipoxygenase (LOX) in the execution of mammalian cell apoptosis, a process which seems to play a critical role also in cell sensitivity to Space conditions. By introducing oxygen into the fatty acid moieties of (phospho)lipids, LOXs can alter fluidity and permeability of biomembranes. Such modifications at the membrane level may play a regulatory role in the physiological clearance mechanism of apoptotic cells.

Original languageEnglish
Title of host publicationEuropean Space Agency, (Special Publication) ESA SP
Pages23-26
Number of pages4
Edition501
Publication statusPublished - Sep 2002
EventProceedings of the European Symposium on Life in Space for Life on Earth - Stockholm, Sweden
Duration: Jun 2 2002Jun 7 2002

Other

OtherProceedings of the European Symposium on Life in Space for Life on Earth
CountrySweden
CityStockholm
Period6/2/026/7/02

ASJC Scopus subject areas

  • Aerospace Engineering

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  • Cite this

    Maccarrone, M., Battista, N., Bari, M., & Finazzi Agrò, A. (2002). Lipoxygenase and apoptosis in microgravity. In European Space Agency, (Special Publication) ESA SP (501 ed., pp. 23-26)