Lithium salts have been for many years the treatment of choice for bipolar disorders especially in the long-term therapy for the prevention of relapses. However it has been recently observed that, when whole bipolar spectrum disorder is considered, the response to lithium salts is not higher than 50%. Moreover the low efficacy of this compound in the mixed mania, in the rapid cycling and in the subtypes with psychotic features and the high number of patients unable to tolerate lithium therapy, led to the introduction of other drugs with mood stabilizing effects in the clinical practice. Several studies have shown the efficacy of carbamazepine and valproate in the acute and prophylactic treatment of bipolar patients.
|Translated title of the contribution||Lithium, carbamazepine an valproate in the treatment of bipolar disorder|
|Number of pages||9|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Issue number||95-96 SUPPL. 1|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Clinical Neurology