Abstract
Purpose: Four-dimensional magnetic resonance imaging (4DMRI) is an emerging technique in radiotherapy treatment planning for organ motion quantification. In this paper, the authors present a novel 4DMRI retrospective image-based sorting method, providing reduced motion artifacts than using a standard monodimensional external respiratory surrogate. Methods: Serial interleaved 2D multislice MRI data were acquired from 24 liver cases (6 volunteers + 18 patients) to test the proposed 4DMRI sorting. Image similarity based on mutual information was applied to automatically identify a stable reference phase and sort the image sequence retrospectively, without the use of additional image or surrogate data to describe breathing motion. Results: The image-based 4DMRI provided a smoother liver profile than that obtained from standard resorting based on an external surrogate. Reduced motion artifacts were observed in image-based 4DMRI datasets with a fitting error of the liver profile measuring 1.2±0.9 mm (median ± interquartile range) vs 2.1±1.7 mm of the standard method. Conclusions: The authors present a novel methodology to derive a patient-specific 4DMRI model to describe organ motion due to breathing, with improved image quality in 4D reconstruction.
| Original language | English |
|---|---|
| Pages (from-to) | 4814-4821 |
| Number of pages | 8 |
| Journal | Medical Physics |
| Volume | 42 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1 2015 |
Fingerprint
Keywords
- 4DMRI
- radiotherapy
- retrospective sorting
- time-resolved imaging
- treatment planning
ASJC Scopus subject areas
- Biophysics
- Radiology Nuclear Medicine and imaging
Cite this
Liver 4DMRI : A retrospective image-based sorting method. / Paganelli, Chiara; Summers, Paul; Bellomi, Massimo; Baroni, Guido; Riboldi, Marco.
In: Medical Physics, Vol. 42, No. 8, 01.08.2015, p. 4814-4821.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Liver 4DMRI
T2 - A retrospective image-based sorting method
AU - Paganelli, Chiara
AU - Summers, Paul
AU - Bellomi, Massimo
AU - Baroni, Guido
AU - Riboldi, Marco
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Purpose: Four-dimensional magnetic resonance imaging (4DMRI) is an emerging technique in radiotherapy treatment planning for organ motion quantification. In this paper, the authors present a novel 4DMRI retrospective image-based sorting method, providing reduced motion artifacts than using a standard monodimensional external respiratory surrogate. Methods: Serial interleaved 2D multislice MRI data were acquired from 24 liver cases (6 volunteers + 18 patients) to test the proposed 4DMRI sorting. Image similarity based on mutual information was applied to automatically identify a stable reference phase and sort the image sequence retrospectively, without the use of additional image or surrogate data to describe breathing motion. Results: The image-based 4DMRI provided a smoother liver profile than that obtained from standard resorting based on an external surrogate. Reduced motion artifacts were observed in image-based 4DMRI datasets with a fitting error of the liver profile measuring 1.2±0.9 mm (median ± interquartile range) vs 2.1±1.7 mm of the standard method. Conclusions: The authors present a novel methodology to derive a patient-specific 4DMRI model to describe organ motion due to breathing, with improved image quality in 4D reconstruction.
AB - Purpose: Four-dimensional magnetic resonance imaging (4DMRI) is an emerging technique in radiotherapy treatment planning for organ motion quantification. In this paper, the authors present a novel 4DMRI retrospective image-based sorting method, providing reduced motion artifacts than using a standard monodimensional external respiratory surrogate. Methods: Serial interleaved 2D multislice MRI data were acquired from 24 liver cases (6 volunteers + 18 patients) to test the proposed 4DMRI sorting. Image similarity based on mutual information was applied to automatically identify a stable reference phase and sort the image sequence retrospectively, without the use of additional image or surrogate data to describe breathing motion. Results: The image-based 4DMRI provided a smoother liver profile than that obtained from standard resorting based on an external surrogate. Reduced motion artifacts were observed in image-based 4DMRI datasets with a fitting error of the liver profile measuring 1.2±0.9 mm (median ± interquartile range) vs 2.1±1.7 mm of the standard method. Conclusions: The authors present a novel methodology to derive a patient-specific 4DMRI model to describe organ motion due to breathing, with improved image quality in 4D reconstruction.
KW - 4DMRI
KW - radiotherapy
KW - retrospective sorting
KW - time-resolved imaging
KW - treatment planning
UR - http://www.scopus.com/inward/record.url?scp=84937905500&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84937905500&partnerID=8YFLogxK
U2 - 10.1118/1.4927252
DO - 10.1118/1.4927252
M3 - Article
C2 - 26233208
AN - SCOPUS:84937905500
VL - 42
SP - 4814
EP - 4821
JO - Medical Physics
JF - Medical Physics
SN - 0094-2405
IS - 8
ER -