A diagnosis of liver cirrhosis, porphyria cutanea tarda and type II diabetes mellitus was made in a person with chronic occupational exposure to a high level of methyl chloride. Two pathogenetic explanations are offered: first, that the clinical picture was the result of occupational exposure to the solvent which caused the onset of porphyria cutanea tarda via a direct toxic mechanism; the second and more likely explanation is that the primary lesion was a chronic liver damage due to occupational exposure to the solvent, which subsequently could have caused the onset of porphyria cutanea tarda. Possible co-operating causes were a history of viral hepatitis and excessive alcohol consumption.
|Translated title of the contribution||Liver cirrhosis and porphyria cutanea tarda in a case of occupational exposure to methyl chloride|
|Number of pages||4|
|Journal||Medicina del Lavoro|
|Publication status||Published - 1982|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health