Liver Illness and Psoriatic Patients

Marco Fiore, Sebastiano Leone, Alberto Enrico Maraolo, Emilio Berti, Giovanni Damiani

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Psoriasis is a chronic inflammatory disease of the skin affecting approximately 2% of the world's population. Systemic treatments, including methotrexate and cyclosporin, are associated with potential hepatotoxicity, due to either direct liver damage or immunosuppression or both immunomediated and a direct liver injury; therefore, treatment of patients with psoriasis poses a therapeutic challenge. The aim of this minireview is to help clinicians in the management of psoriatic patients who develop signs of liver dysfunction. To find relevant articles, a comprehensive search was performed on PubMed, EMBASE, and Cochrane with appropriate combinations of the following keywords being considered: Viral hepatitis, nonalcoholic fatty liver disease, psoriasis, hepatotoxicity, drug toxicity, cholestasis, and autoimmune liver diseases.

Original languageEnglish
Article number3140983
JournalBioMed Research International
Volume2018
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Psoriasis
Liver
Liver Diseases
Cholestasis
Drug-Related Side Effects and Adverse Reactions
PubMed
Methotrexate
Immunosuppression
Cyclosporine
Hepatitis
Autoimmune Diseases
Chronic Disease
Therapeutics
Skin
Wounds and Injuries
Toxicity
Population
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Fiore, M., Leone, S., Maraolo, A. E., Berti, E., & Damiani, G. (2018). Liver Illness and Psoriatic Patients. BioMed Research International, 2018, [3140983]. https://doi.org/10.1155/2018/3140983

Liver Illness and Psoriatic Patients. / Fiore, Marco; Leone, Sebastiano; Maraolo, Alberto Enrico; Berti, Emilio; Damiani, Giovanni.

In: BioMed Research International, Vol. 2018, 3140983, 01.01.2018.

Research output: Contribution to journalReview article

Fiore, M, Leone, S, Maraolo, AE, Berti, E & Damiani, G 2018, 'Liver Illness and Psoriatic Patients', BioMed Research International, vol. 2018, 3140983. https://doi.org/10.1155/2018/3140983
Fiore, Marco ; Leone, Sebastiano ; Maraolo, Alberto Enrico ; Berti, Emilio ; Damiani, Giovanni. / Liver Illness and Psoriatic Patients. In: BioMed Research International. 2018 ; Vol. 2018.
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