Liver involvement in Sjögren’s syndrome

George E. Fragoulis, Fotini N. Skopouli, Carlo Selmi, M. Eric Gershwin

Research output: Chapter in Book/Report/Conference proceedingChapter


Liver involvement in Sjögren’s syndrome (SS) is commonly subclinical and almost never appears as the first manifestation of the disease. The prevalence of liver involvement in SS varies among series and depends on the diagnostic criteria used. Studies conducted in the 1960s, based on clinical (i.e., liver enlargement) and serological (i.e., elevated alkaline phosphatase) findings estimated the SS liver involvement as high as 20% [1]. A somewhat lower prevalence of liver disease has been reported in more recent studies, with estimates ranging from 2% to 20% of SS patients [2–6].

Original languageEnglish
Title of host publicationSjogren's Syndrome: Diagnosis and Therapeutics
PublisherSpringer-Verlag London Ltd
Number of pages10
ISBN (Print)9780857299475, 9780857299468
Publication statusPublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)


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