Liver metastases: Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance

Vito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Fabrizio Calliada, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The development of ultrasound contrast agents with excellent tolerance and safety profiles has notably improved liver evaluation with ultrasound (US) for several applications, especially for the detection of metastases. In particular, contrast enhanced ultrasonography (CEUS) allows the display of the parenchymal microvasculature, enabling the study and visualization of the enhancement patterns of liver lesions in real time and in a continuous manner in all vascular phases, which is similar to contrast-enhanced computed tomography (CT) and contrast-enhanced magnetic resonance imaging. Clinical studies have reported that the use of a contrast agent enables the visualization of more metastases with significantly improved sensitivity and specificity compared to baseline-US. Furthermore, studies have shown that CEUS yields sensitivities comparable to CT. In this review, we describe the state of the art of CEUS for detecting colorectal liver metastases, the imaging features, the literature reports of metastases in CEUS as well as its technique, its clinical role and its potential applications. Additionally, the updated international consensus panel guidelines are reported in this review with the inherent limitations of this technique and best practice experiences.

Original languageEnglish
Pages (from-to)9998-10007
Number of pages10
JournalWorld Journal of Gastroenterology
Issue number29
DOIs
Publication statusPublished - Aug 7 2014

Fingerprint

Ultrasonography
Magnetic Resonance Spectroscopy
Tomography
Neoplasm Metastasis
Liver
Contrast Media
Microvessels
Practice Guidelines
Blood Vessels
Magnetic Resonance Imaging
Guidelines
Safety
Sensitivity and Specificity

Keywords

  • <sup>18</sup>F-fluorodeoxyglucose positron emission tomography
  • Colorectal cancer
  • Colorectal liver metastases
  • Computed tomography
  • Contrast enhanced ultrasound
  • Intraoperative ultrasound
  • Magnetic resonance imaging
  • Ultrasound
  • Ultrasound contrast agent

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Liver metastases : Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance. / Cantisani, Vito; Grazhdani, Hektor; Fioravanti, Cristina; Rosignuolo, Maria; Calliada, Fabrizio; Messineo, Daniela; Bernieri, Maria Giulia; Redler, Adriano; Catalano, Carlo; D'Ambrosio, Ferdinando.

In: World Journal of Gastroenterology, No. 29, 07.08.2014, p. 9998-10007.

Research output: Contribution to journalArticle

Cantisani, V, Grazhdani, H, Fioravanti, C, Rosignuolo, M, Calliada, F, Messineo, D, Bernieri, MG, Redler, A, Catalano, C & D'Ambrosio, F 2014, 'Liver metastases: Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance', World Journal of Gastroenterology, no. 29, pp. 9998-10007. https://doi.org/10.3748/wjg.v20.i29.9998
Cantisani, Vito ; Grazhdani, Hektor ; Fioravanti, Cristina ; Rosignuolo, Maria ; Calliada, Fabrizio ; Messineo, Daniela ; Bernieri, Maria Giulia ; Redler, Adriano ; Catalano, Carlo ; D'Ambrosio, Ferdinando. / Liver metastases : Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance. In: World Journal of Gastroenterology. 2014 ; No. 29. pp. 9998-10007.
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