TY - JOUR
T1 - Liver resection for hepatic metastases
T2 - 15 years of experience
AU - Belli, Giulio
AU - D'Agostino, Alberto
AU - Ciciliano, Fabio
AU - Fantini, Corrado
AU - Russolillo, Nadia
AU - Belli, Andrea
PY - 2002
Y1 - 2002
N2 - Background/Purpose. Liver metastases, especially those from primary colorectal cancers, are treatable and potentially curable. Imaging techniques such as computed tomography, magnetic resonance, and ultrasonography have advanced in recent years and led to increased sensitivity and specificity in the diagnosis of liver metastases. Liver surgery also has been revolutionized in the past two decades. Dissection along nonanatomical lines has permitted the resection of multiple lesions that previously might have been considered unresectable. Methods. From 1986 to 2000, 181 patients underwent liver resection for hepatic metastasis from colorectal cancer. Of these, 56 patients underwent systematic anatomical major hepatic resection and 125 underwent nonanatomical limited resection. Results. Operative morbidity and mortality rates were higher in patients in whom anatomical procedures were performed. The overall 5-year survival rate of the 181 patients Was 39.8%. Conclusions. An aggressive surgical procedure in patients with hepatic colorectal metastases is safe, and may prolong overall survival, and therefore should be considered in all patients with metastases confined to the liver.
AB - Background/Purpose. Liver metastases, especially those from primary colorectal cancers, are treatable and potentially curable. Imaging techniques such as computed tomography, magnetic resonance, and ultrasonography have advanced in recent years and led to increased sensitivity and specificity in the diagnosis of liver metastases. Liver surgery also has been revolutionized in the past two decades. Dissection along nonanatomical lines has permitted the resection of multiple lesions that previously might have been considered unresectable. Methods. From 1986 to 2000, 181 patients underwent liver resection for hepatic metastasis from colorectal cancer. Of these, 56 patients underwent systematic anatomical major hepatic resection and 125 underwent nonanatomical limited resection. Results. Operative morbidity and mortality rates were higher in patients in whom anatomical procedures were performed. The overall 5-year survival rate of the 181 patients Was 39.8%. Conclusions. An aggressive surgical procedure in patients with hepatic colorectal metastases is safe, and may prolong overall survival, and therefore should be considered in all patients with metastases confined to the liver.
KW - Colorectal cancer
KW - Hepatic metastases
KW - Liver resection
UR - http://www.scopus.com/inward/record.url?scp=0036923725&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036923725&partnerID=8YFLogxK
U2 - 10.1007/s005340200082
DO - 10.1007/s005340200082
M3 - Article
C2 - 12541048
AN - SCOPUS:0036923725
VL - 9
SP - 607
EP - 613
JO - Journal of Hepato-Biliary-Pancreatic Sciences
JF - Journal of Hepato-Biliary-Pancreatic Sciences
SN - 0944-1166
IS - 5
ER -