Liver resection for hepatocellular carcinoma in cirrhotic patients

G. Gozzetti, L. Belli, L. Capussotti, V. Di Carlo, L. Gennari, A. Maffei Faccioli, A. Mazziotti, P. Spina, H. Bouzari, M. Dellepiane, G. Gerunda, G. L. Grazi, E. Jovine, C. Marenghi, F. Montalto, E. Regalia, E. Opocher, F. Riolo, F. Romani

Research output: Contribution to journalArticlepeer-review


The results of a multicentric retrospective analysis of 265 liver resections for hepatocellular carcinoma in cirrhotic patients have been collected and assessed. Overall operative mortality was 9.1%. The actuarial 3-year survival was 46.5%. Better results were obtained in patients with encapsulated lesions and alphafetoprotein levels less than 400 ng/dl. Tumoral recurrence, which was the main cause of late death, was related to alphafetoprotein higher levels and to the type of surgery performed: tumorectomies with short tumour free margin had the highest recurrence rate. Results were significantly better in those centers where intraoperative ultrasonography was siste-matically employed.

Original languageEnglish
Pages (from-to)105-110
Number of pages6
JournalItalian Journal of Gastroenterology
Issue number2
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Gastroenterology


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