Liver resection in the treatment of hepatocellular carcinoma

Dario Ribero, Eddie K. Abdalla, Melanie B. Thomas, Jean Nicolas Vauthey

Research output: Contribution to journalArticlepeer-review

Abstract

Hepatocellular carcinoma is a leading cause of cancer death worldwide. Liver resection and liver transplantation remain the only options for cure. Since the indications for orthotopic liver transplantation are limited, partial liver resection is the more common treatment. Recently, indications for liver resection have been expanded and there have been advances in the associated surgical techniques. This review describes the state-of-the-art of liver resection for hepatocellular carcinoma. Topics covered include: new indications, such as treatment of large tumors, bilobar tumors and those associated with vascular invasion; preoperative assessment of liver function; and surgical strategies. An overview of the most common staging systems, which are useful in predicting prognosis after liver resection for hepatocellular carcinoma, is given.

Original languageEnglish
Pages (from-to)567-579
Number of pages13
JournalExpert Review of Anticancer Therapy
Volume6
Issue number4
DOIs
Publication statusPublished - Apr 2006

Keywords

  • Embolization
  • Fibrosis
  • Hepatitis
  • Hepatocellular carcinoma
  • Portal vein
  • Resection
  • Transplantation

ASJC Scopus subject areas

  • Pharmacology
  • Cancer Research

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