Liver resection without blood transfusion

G. Gozzetti, A. Mazziotti, G. L. Grazi, E. Jovine, A. Gallucci, S. Gruttadauria, A. Frena, M. Morganti, G. Ercolani, M. Masetti, F. Pierangeli

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Abstract

A retrospective study was carried out of 522 elective liver resections to determine the impact of blood transfusion on the immediate postoperative outcome and on long-term survival. The number of liver resections without transfusion has increased in recent years, as a result of improvement in surgical technique with less blood loss during operation and more careful choice of the timing of transfusion. In resections carried out in the past 5 years, the indication for intraoperative transfusion was restricted and the decision was made jointly by the surgeon and anaesthetist, and in any case only if the haematocrit was below 25 per cent. Of resections carried out in the past 2 years, 59 per cent did not require intraoperative transfusion. Postoperative deaths and complications were related to blood transfusion, particularly in patients with cirrhosis, in whom stepwise logistic regression analysis showed that transfusion was the only factor that correlated significantly with complications. Transfusion also affected the long-term survival of patients operated on for hepatocellular carcinoma and colorectal carcinoma metastases in univariate analysis and was the only factor shown by multivariate analysis to correlate with survival for hepatocellular carcinoma in patients with cirrhosis.

Original languageEnglish
Pages (from-to)1105-1110
Number of pages6
JournalBritish Journal of Surgery
Volume82
Issue number8
DOIs
Publication statusPublished - 1995

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Blood Transfusion
Survival
Hepatocellular Carcinoma
Liver
Fibrosis
Hematocrit
Colorectal Neoplasms
Multivariate Analysis
Retrospective Studies
Logistic Models
Regression Analysis
Neoplasm Metastasis
Anesthetists
Surgeons

ASJC Scopus subject areas

  • Surgery

Cite this

Gozzetti, G., Mazziotti, A., Grazi, G. L., Jovine, E., Gallucci, A., Gruttadauria, S., ... Pierangeli, F. (1995). Liver resection without blood transfusion. British Journal of Surgery, 82(8), 1105-1110. https://doi.org/10.1002/bjs.1800820833

Liver resection without blood transfusion. / Gozzetti, G.; Mazziotti, A.; Grazi, G. L.; Jovine, E.; Gallucci, A.; Gruttadauria, S.; Frena, A.; Morganti, M.; Ercolani, G.; Masetti, M.; Pierangeli, F.

In: British Journal of Surgery, Vol. 82, No. 8, 1995, p. 1105-1110.

Research output: Contribution to journalArticle

Gozzetti, G, Mazziotti, A, Grazi, GL, Jovine, E, Gallucci, A, Gruttadauria, S, Frena, A, Morganti, M, Ercolani, G, Masetti, M & Pierangeli, F 1995, 'Liver resection without blood transfusion', British Journal of Surgery, vol. 82, no. 8, pp. 1105-1110. https://doi.org/10.1002/bjs.1800820833
Gozzetti, G. ; Mazziotti, A. ; Grazi, G. L. ; Jovine, E. ; Gallucci, A. ; Gruttadauria, S. ; Frena, A. ; Morganti, M. ; Ercolani, G. ; Masetti, M. ; Pierangeli, F. / Liver resection without blood transfusion. In: British Journal of Surgery. 1995 ; Vol. 82, No. 8. pp. 1105-1110.
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