Abstract
A retrospective study was carried out of 522 elective liver resections to determine the impact of blood transfusion on the immediate postoperative outcome and on long-term survival. The number of liver resections without transfusion has increased in recent years, as a result of improvement in surgical technique with less blood loss during operation and more careful choice of the timing of transfusion. In resections carried out in the past 5 years, the indication for intraoperative transfusion was restricted and the decision was made jointly by the surgeon and anaesthetist, and in any case only if the haematocrit was below 25 per cent. Of resections carried out in the past 2 years, 59 per cent did not require intraoperative transfusion. Postoperative deaths and complications were related to blood transfusion, particularly in patients with cirrhosis, in whom stepwise logistic regression analysis showed that transfusion was the only factor that correlated significantly with complications. Transfusion also affected the long-term survival of patients operated on for hepatocellular carcinoma and colorectal carcinoma metastases in univariate analysis and was the only factor shown by multivariate analysis to correlate with survival for hepatocellular carcinoma in patients with cirrhosis.
| Original language | English |
|---|---|
| Pages (from-to) | 1105-1110 |
| Number of pages | 6 |
| Journal | British Journal of Surgery |
| Volume | 82 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1995 |
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ASJC Scopus subject areas
- Surgery
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Liver resection without blood transfusion. / Gozzetti, G.; Mazziotti, A.; Grazi, G. L.; Jovine, E.; Gallucci, A.; Gruttadauria, S.; Frena, A.; Morganti, M.; Ercolani, G.; Masetti, M.; Pierangeli, F.
In: British Journal of Surgery, Vol. 82, No. 8, 1995, p. 1105-1110.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Liver resection without blood transfusion
AU - Gozzetti, G.
AU - Mazziotti, A.
AU - Grazi, G. L.
AU - Jovine, E.
AU - Gallucci, A.
AU - Gruttadauria, S.
AU - Frena, A.
AU - Morganti, M.
AU - Ercolani, G.
AU - Masetti, M.
AU - Pierangeli, F.
PY - 1995
Y1 - 1995
N2 - A retrospective study was carried out of 522 elective liver resections to determine the impact of blood transfusion on the immediate postoperative outcome and on long-term survival. The number of liver resections without transfusion has increased in recent years, as a result of improvement in surgical technique with less blood loss during operation and more careful choice of the timing of transfusion. In resections carried out in the past 5 years, the indication for intraoperative transfusion was restricted and the decision was made jointly by the surgeon and anaesthetist, and in any case only if the haematocrit was below 25 per cent. Of resections carried out in the past 2 years, 59 per cent did not require intraoperative transfusion. Postoperative deaths and complications were related to blood transfusion, particularly in patients with cirrhosis, in whom stepwise logistic regression analysis showed that transfusion was the only factor that correlated significantly with complications. Transfusion also affected the long-term survival of patients operated on for hepatocellular carcinoma and colorectal carcinoma metastases in univariate analysis and was the only factor shown by multivariate analysis to correlate with survival for hepatocellular carcinoma in patients with cirrhosis.
AB - A retrospective study was carried out of 522 elective liver resections to determine the impact of blood transfusion on the immediate postoperative outcome and on long-term survival. The number of liver resections without transfusion has increased in recent years, as a result of improvement in surgical technique with less blood loss during operation and more careful choice of the timing of transfusion. In resections carried out in the past 5 years, the indication for intraoperative transfusion was restricted and the decision was made jointly by the surgeon and anaesthetist, and in any case only if the haematocrit was below 25 per cent. Of resections carried out in the past 2 years, 59 per cent did not require intraoperative transfusion. Postoperative deaths and complications were related to blood transfusion, particularly in patients with cirrhosis, in whom stepwise logistic regression analysis showed that transfusion was the only factor that correlated significantly with complications. Transfusion also affected the long-term survival of patients operated on for hepatocellular carcinoma and colorectal carcinoma metastases in univariate analysis and was the only factor shown by multivariate analysis to correlate with survival for hepatocellular carcinoma in patients with cirrhosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0029098317&partnerID=8YFLogxK
U2 - 10.1002/bjs.1800820833
DO - 10.1002/bjs.1800820833
M3 - Article
C2 - 7648166
AN - SCOPUS:0029098317
VL - 82
SP - 1105
EP - 1110
JO - British Journal of Surgery
JF - British Journal of Surgery
SN - 0007-1323
IS - 8
ER -