Liver transplantation for HBV-related cirrhosis in Europe: An ELTR study on evolution and outcomes

Patrizia Burra, Giacomo Germani, Renè Adam, Vincent Karam, Alfredo Marzano, Pietro Lampertico, Mauro Salizzoni, Franco Filipponi, Jurgen L. Klempnauer, Denis Castaing, Murat Kilic, Luciano De Carlis, Peter Neuhaus, Sezai Yilmaz, Andreas Paul, Antonio D. Pinna, Andrew K. Burroughs, Francesco P. Russo

Research output: Contribution to journalArticle

Abstract

Background & Aims: HBV-related chronic liver disease is one of the most common indications for liver transplantation (LT) in Europe. The ELTR database was used to evaluate outcomes and evolution over 20 years (01/1988 and 12/2010). Methods: HBV transplanted patients were analysed according to indication for LT: decompensated cirrhosis (HBVdec) or hepatocellular carcinoma (HBV/HCC). These groups were compared with co-infected patients HBV/HDV (HBDV), HBV/HCV (HBCV), HBV/HDV/HCV (HBDCV); n = 16,664 and with HCV patients (n = 2452) according to LT indication. Results: 5912 patients were transplanted for HBV (78% HBVdec, 22% HBV/HCC), with HBV/HCC patients who increased from 15.8% in 1988-1995 to 29.6% in 2006-2010 (p

Original languageEnglish
Pages (from-to)287-296
Number of pages10
JournalJournal of Hepatology
Volume58
Issue number2
DOIs
Publication statusPublished - Feb 2013

Keywords

  • Europe
  • Hepatitis B
  • Liver transplantation

ASJC Scopus subject areas

  • Hepatology

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    Burra, P., Germani, G., Adam, R., Karam, V., Marzano, A., Lampertico, P., Salizzoni, M., Filipponi, F., Klempnauer, J. L., Castaing, D., Kilic, M., Carlis, L. D., Neuhaus, P., Yilmaz, S., Paul, A., Pinna, A. D., Burroughs, A. K., & Russo, F. P. (2013). Liver transplantation for HBV-related cirrhosis in Europe: An ELTR study on evolution and outcomes. Journal of Hepatology, 58(2), 287-296. https://doi.org/10.1016/j.jhep.2012.10.016