Liver transplantation for refractory severe pruritus related to widespread multifocal hepatic focal nodular hyperplasia (FNH) in a child: Case report and review of literature

L. Merli, C. Grimaldi, L. Monti, V. Nobili, P. Francalanci, J. De Ville De Goyet

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2 Citations (Scopus)

Abstract

FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.

Original languageEnglish
JournalPediatric Transplantation
Volume16
Issue number7
DOIs
Publication statusPublished - Nov 2012

Fingerprint

Focal Nodular Hyperplasia
Pruritus
Liver Transplantation
Liver
Neoplasms
Transplantation
Transplants

Keywords

  • benign liver tumor
  • focal nodular hyperplasia
  • liver transplantation
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

Cite this

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abstract = "FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.",
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T1 - Liver transplantation for refractory severe pruritus related to widespread multifocal hepatic focal nodular hyperplasia (FNH) in a child

T2 - Case report and review of literature

AU - Merli, L.

AU - Grimaldi, C.

AU - Monti, L.

AU - Nobili, V.

AU - Francalanci, P.

AU - De Ville De Goyet, J.

PY - 2012/11

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N2 - FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.

AB - FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.

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KW - focal nodular hyperplasia

KW - liver transplantation

KW - pediatric

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