Liver transplantation in Italy: Preliminary 10-year report

S. Fagiuoli, G. Leandro, G. Bellati, A. Gasbarrini, G. L. Rapaccini, M. Pompili, M. Rendina, S. De Notariis, A. Franca Villa, G. Gasbarrini, G. Ideo, R. Naccarato

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Experience in liver transplantation (OLT) in Italy over a ten-year period is reported. Data were obtained using a multiple-items form collected from Italian liver transplant centres (reference centres) and other Italian institutions actively involved both in the processes of evaluation of the candidates and the follow-up of liver transplant recipients (afference centres). During this period, a total of 1046 liver transplants were performed on 954 patients, with a cumulative proportional survival of 71%. The most common indication for liver transplantation was post-hepatitic cirrhosis due to either hepatitis B virus (+/- hepatitis Delta virus) or hepatitis C virus infection. Good survival rates were observed, particularly in controversial indications, such as alcoholic cirrhosis, post-hepatitic hepatitis B virus-related cirrhosis and hepatocellular carcinoma, most likely due to proper and careful selection of the patients. Cirrhosis, secondary to an autoimmunity-based liver disease, showed the highest rate of rejection episodes. Infections, in our study population, were the most common cause of death after transplantation.

Original languageEnglish
Pages (from-to)343-350
Number of pages8
JournalItalian Journal of Gastroenterology
Issue number6
Publication statusPublished - 1996


  • Liver disease
  • Liver transplantation
  • Rejection

ASJC Scopus subject areas

  • Gastroenterology


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