Liver transplantation in Italy: Preliminary 10-year report

S. Fagiuoli, G. Leandro, G. Bellati, A. Gasbarrini, G. L. Rapaccini, M. Pompili, M. Rendina, S. De Notariis, A. Franca Villa, G. Gasbarrini, G. Ideo, R. Naccarato

Research output: Contribution to journalArticlepeer-review

Abstract

Experience in liver transplantation (OLT) in Italy over a ten-year period is reported. Data were obtained using a multiple-items form collected from Italian liver transplant centres (reference centres) and other Italian institutions actively involved both in the processes of evaluation of the candidates and the follow-up of liver transplant recipients (afference centres). During this period, a total of 1046 liver transplants were performed on 954 patients, with a cumulative proportional survival of 71%. The most common indication for liver transplantation was post-hepatitic cirrhosis due to either hepatitis B virus (+/- hepatitis Delta virus) or hepatitis C virus infection. Good survival rates were observed, particularly in controversial indications, such as alcoholic cirrhosis, post-hepatitic hepatitis B virus-related cirrhosis and hepatocellular carcinoma, most likely due to proper and careful selection of the patients. Cirrhosis, secondary to an autoimmunity-based liver disease, showed the highest rate of rejection episodes. Infections, in our study population, were the most common cause of death after transplantation.

Original languageEnglish
Pages (from-to)343-350
Number of pages8
JournalItalian Journal of Gastroenterology
Volume28
Issue number6
Publication statusPublished - 1996

Keywords

  • Liver disease
  • Liver transplantation
  • Rejection

ASJC Scopus subject areas

  • Gastroenterology

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