Localization of α-bungarotoxin binding sites within the rat corpus striatum

F. Amenta; G. Bernardi; V. Floris; M. G. Marciani

doi:10.1016/0028-3908(79)90133-3

Localization of α-bungarotoxin binding sites within the rat corpus striatum

F. Amenta, G. Bernardi, V. Floris, M. G. Marciani

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Nicotinic cholinergic receptors (NChR) in rat corpus striatum were studied by the use of fluorescent α-bungarotoxin (αFBTx), a potent nicotinic antagonist and by the immunofluorescence. The corpus striatum is poor of these receptors. These results do not support the hypothesis that the acetylcholine (Ach), with nicotinic action, modulates presynaptically the dopamine (DA) release from the axon terminals of the nigrostriatal projection.

Original language	English
Pages (from-to)	319-322
Number of pages	4
Journal	Neuropharmacology
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/0028-3908(79)90133-3
Publication status	Published - 1979

ASJC Scopus subject areas

Cellular and Molecular Neuroscience
Drug Discovery
Pharmacology

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AU - Bernardi, G.

AU - Floris, V.

AU - Marciani, M. G.

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AB - Nicotinic cholinergic receptors (NChR) in rat corpus striatum were studied by the use of fluorescent α-bungarotoxin (αFBTx), a potent nicotinic antagonist and by the immunofluorescence. The corpus striatum is poor of these receptors. These results do not support the hypothesis that the acetylcholine (Ach), with nicotinic action, modulates presynaptically the dopamine (DA) release from the axon terminals of the nigrostriatal projection.

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Localization of α-bungarotoxin binding sites within the rat corpus striatum

Abstract

ASJC Scopus subject areas

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