Localization of α-bungarotoxin binding sites within the rat corpus striatum

F. Amenta, G. Bernardi, V. Floris, M. G. Marciani

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Nicotinic cholinergic receptors (NChR) in rat corpus striatum were studied by the use of fluorescent α-bungarotoxin (αFBTx), a potent nicotinic antagonist and by the immunofluorescence. The corpus striatum is poor of these receptors. These results do not support the hypothesis that the acetylcholine (Ach), with nicotinic action, modulates presynaptically the dopamine (DA) release from the axon terminals of the nigrostriatal projection.

Original languageEnglish
Pages (from-to)319-322
Number of pages4
JournalNeuropharmacology
Volume18
Issue number3
DOIs
Publication statusPublished - 1979

Fingerprint

Corpus Striatum
Bungarotoxins
Binding Sites
Nicotinic Antagonists
Presynaptic Terminals
Nicotinic Receptors
Cholinergic Receptors
Acetylcholine
Fluorescent Antibody Technique
Dopamine

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Drug Discovery
  • Pharmacology

Cite this

Localization of α-bungarotoxin binding sites within the rat corpus striatum. / Amenta, F.; Bernardi, G.; Floris, V.; Marciani, M. G.

In: Neuropharmacology, Vol. 18, No. 3, 1979, p. 319-322.

Research output: Contribution to journalArticle

Amenta, F. ; Bernardi, G. ; Floris, V. ; Marciani, M. G. / Localization of α-bungarotoxin binding sites within the rat corpus striatum. In: Neuropharmacology. 1979 ; Vol. 18, No. 3. pp. 319-322.
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