Nicotinic cholinergic receptors (NChR) in rat corpus striatum were studied by the use of fluorescent α-bungarotoxin (αFBTx), a potent nicotinic antagonist and by the immunofluorescence. The corpus striatum is poor of these receptors. These results do not support the hypothesis that the acetylcholine (Ach), with nicotinic action, modulates presynaptically the dopamine (DA) release from the axon terminals of the nigrostriatal projection.
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience
- Drug Discovery