Localization of factor VIII-related antigen in the endothelium of the chick embryo chorioallantoic membrane

Domenico Ribatti, Beatrice Nico, Angelo Vacca, Luisa Roncali

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In this study, by using a polyclonal antibody against factor VIII- related antigen (FVIII-RA), we have examined the expression of FVIII-RA in the blood and lymphatic vessels of the chick embryo chorioallantoic membrane (CAM). The antibody marked the endothelium of blood and lymphatic vessels starting from day 8 of incubation and the cytoplasm of the allantoic epithelial cells. The application of this antibody may be useful for quantifying neovascularization in response to various angiogenic stimuli applied to the CAM.

Original languageEnglish
Pages (from-to)447-450
Number of pages4
JournalHistochemistry and Cell Biology
Issue number6
Publication statusPublished - 1999


ASJC Scopus subject areas

  • Cell Biology
  • Instrumentation

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