Localization of factor VIII-related antigen in the endothelium of the chick embryo chorioallantoic membrane

Domenico Ribatti, Beatrice Nico, Angelo Vacca, Luisa Roncali

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

In this study, by using a polyclonal antibody against factor VIII- related antigen (FVIII-RA), we have examined the expression of FVIII-RA in the blood and lymphatic vessels of the chick embryo chorioallantoic membrane (CAM). The antibody marked the endothelium of blood and lymphatic vessels starting from day 8 of incubation and the cytoplasm of the allantoic epithelial cells. The application of this antibody may be useful for quantifying neovascularization in response to various angiogenic stimuli applied to the CAM.

Original languageEnglish
Pages (from-to)447-450
Number of pages4
JournalHistochemistry and Cell Biology
Volume112
Issue number6
Publication statusPublished - 1999

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endothelium
Chorioallantoic Membrane
embryos
von Willebrand Factor
antigens
Chick Embryo
Antigens
antibodies
Antibodies
Endothelium
Lymphatic Vessels
blood vessels
membranes
Membranes
vessels
Blood Vessels
Blood
angiogenesis
cytoplasm
stimuli

ASJC Scopus subject areas

  • Cell Biology
  • Instrumentation

Cite this

Localization of factor VIII-related antigen in the endothelium of the chick embryo chorioallantoic membrane. / Ribatti, Domenico; Nico, Beatrice; Vacca, Angelo; Roncali, Luisa.

In: Histochemistry and Cell Biology, Vol. 112, No. 6, 1999, p. 447-450.

Research output: Contribution to journalArticle

Ribatti, Domenico ; Nico, Beatrice ; Vacca, Angelo ; Roncali, Luisa. / Localization of factor VIII-related antigen in the endothelium of the chick embryo chorioallantoic membrane. In: Histochemistry and Cell Biology. 1999 ; Vol. 112, No. 6. pp. 447-450.
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