Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells

Daniele D'Ambrosio, Andrea Iellem, Lucia Colantonio, Barbara Clissi, Ruggero Pardi, Francesco Sinigaglia

Research output: Contribution to journalArticle

Abstract

The recruitment of T helper 1 (Th1) and Th2 cells into peripheral tissues is essential for inflammation and the host response to infections. Here, Daniele D'Ambrosio and colleagues review the traffic signals that enable the distinct positioning of Th1 and Th2 cells and argue that differential thresholds for extravasation constitute a critical aspect of their selective localization to inflamed tissues.

Original languageEnglish
Pages (from-to)183-186
Number of pages4
JournalImmunology Today
Volume21
Issue number4
DOIs
Publication statusPublished - Apr 1 2000

ASJC Scopus subject areas

  • Immunology

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