Localized erosive pustular dermatosis of the scalp at the site of a cochlear implant

Successful treatment with topical tacrolimus

A. V. Marzano, M. Ghislanzoni, A. Zaghis, D. Spinelli, C. Crosti

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Erosive pustular dermatosis of the scalp (EPDS) is a rare form of nonmicrobial pustulosis mainly occurring in elderly patients with long-term sun damage to the skin. Clinically, it is characterized by pustular lesions that progressively merge into erosive and crusted areas over the scalp. The histology of EPDS is nonspecific, and its pathophysiology remains undetermined, with various types of local trauma possibly acting as the triggering factor. We describe a 24-year-old woman who developed EPDS after cochlear implant surgery for profound sensorineural hearing loss. We speculate that either the cutaneous surgery during cochlear implantation or the skin inflammation that commonly occurs near the magnet might have triggered the disorder. It is of note that the patient's skin lesions healed completely after treatment with topical tacrolimus, a relatively novel immunosuppressive molecule. Thus, topical tacrolimus may be indicated as a therapeutic alternative to the widely used steroids for this disease, mainly to avoid steroid-related cutaneous atrophy.

Original languageEnglish
JournalClinical and Experimental Dermatology
Volume34
Issue number5
DOIs
Publication statusPublished - Jul 2009

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Scalp Dermatoses
Cochlear Implants
Tacrolimus
Skin
Steroids
Dermatologic Surgical Procedures
Cochlear Implantation
Magnets
Sensorineural Hearing Loss
Solar System
Therapeutics
Immunosuppressive Agents
Scalp
Atrophy
Histology
Inflammation
Wounds and Injuries

ASJC Scopus subject areas

  • Dermatology

Cite this

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abstract = "Erosive pustular dermatosis of the scalp (EPDS) is a rare form of nonmicrobial pustulosis mainly occurring in elderly patients with long-term sun damage to the skin. Clinically, it is characterized by pustular lesions that progressively merge into erosive and crusted areas over the scalp. The histology of EPDS is nonspecific, and its pathophysiology remains undetermined, with various types of local trauma possibly acting as the triggering factor. We describe a 24-year-old woman who developed EPDS after cochlear implant surgery for profound sensorineural hearing loss. We speculate that either the cutaneous surgery during cochlear implantation or the skin inflammation that commonly occurs near the magnet might have triggered the disorder. It is of note that the patient's skin lesions healed completely after treatment with topical tacrolimus, a relatively novel immunosuppressive molecule. Thus, topical tacrolimus may be indicated as a therapeutic alternative to the widely used steroids for this disease, mainly to avoid steroid-related cutaneous atrophy.",
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T1 - Localized erosive pustular dermatosis of the scalp at the site of a cochlear implant

T2 - Successful treatment with topical tacrolimus

AU - Marzano, A. V.

AU - Ghislanzoni, M.

AU - Zaghis, A.

AU - Spinelli, D.

AU - Crosti, C.

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