Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine: A clinical case

Claudia Bareggi; Daniela Paleari; Marina Chiara Garassino; Monica Mora; Silvia Salamina; Monica Senecione; Antonio Ghidini; Gianfranco Pancera

Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine: A clinical case

Claudia Bareggi, Daniela Paleari, Marina Chiara Garassino, Monica Mora, Silvia Salamina, Monica Senecione, Antonio Ghidini, Gianfranco Pancera

Research output: Contribution to journal › Article › peer-review

Abstract

Hand-foot syndrome is a toxic effect of some chemotherapy agents such as 5-fluorouracil (5-FU), capecitabine and liposomal doxorubicin. The symptoms and signs are localized erythema and paresthesia. Floxuridine (FUDR) is an analogue of 5-FU, used for arterial hepatic infusion in patients affected by liver metastases from colorectal cancer. A patient who was treated for colorectal cancer with liver metastases underwent locoregional chemotherapy with FUDR and systemic chemotherapy with FOLFOX4. After three cycles he developed severe painful dermatitis of the right leg. Abdominal X-ray showed displacement of the catheter to the right common iliac artery. Treatment was discontinued and the patient had a rapid recovery.

Original language	English
Pages (from-to)	193-196
Number of pages	4
Journal	Tumori
Volume	91
Issue number	2
Publication status	Published - Mar 2005

Keywords

Arterial hepatic infusion
Floxuridine
Hand-foot syndrome

ASJC Scopus subject areas

Cancer Research

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Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine : A clinical case. / Bareggi, Claudia; Paleari, Daniela; Garassino, Marina Chiara; Mora, Monica; Salamina, Silvia; Senecione, Monica; Ghidini, Antonio; Pancera, Gianfranco.

In: Tumori, Vol. 91, No. 2, 03.2005, p. 193-196.

Research output: Contribution to journal › Article › peer-review

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AU - Mora, Monica

AU - Salamina, Silvia

AU - Senecione, Monica

AU - Ghidini, Antonio

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AB - Hand-foot syndrome is a toxic effect of some chemotherapy agents such as 5-fluorouracil (5-FU), capecitabine and liposomal doxorubicin. The symptoms and signs are localized erythema and paresthesia. Floxuridine (FUDR) is an analogue of 5-FU, used for arterial hepatic infusion in patients affected by liver metastases from colorectal cancer. A patient who was treated for colorectal cancer with liver metastases underwent locoregional chemotherapy with FUDR and systemic chemotherapy with FOLFOX4. After three cycles he developed severe painful dermatitis of the right leg. Abdominal X-ray showed displacement of the catheter to the right common iliac artery. Treatment was discontinued and the patient had a rapid recovery.

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Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine: A clinical case

Abstract

Keywords

ASJC Scopus subject areas

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