Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor: A case report

Research output: Contribution to journalArticle

Abstract

Intra-abdominal fibromatosis (IAF) is a benign mesenchymal lesion that can occur throughout the gastrointestinal tract. Although rare, it is the most common primary tumor of the mesentery and can develop at any age. We describe a rare case of primary IAF involving the mesentery and small bowel which clinically, macroscopically and histologically mimicked malignant gastrointestinal stromal tumor (GIST). This report highlights the fact that benign IAF can be misdiagnosed as a malignant GIST localized in the mesentery or arising from the intestinal wall. Their diagnostic discrimination is essential because of their very different biological behaviors and the fact that the introduction of effective therapies involving tyrosine kinase inhibitor STI571 (imatinib mesylate) has greatly changed the clinical approach to intra-abdominal stromal spindle cell tumors.

Original languageEnglish
Pages (from-to)5226-5528
Number of pages303
JournalWorld Journal of Gastroenterology
Volume11
Issue number33
Publication statusPublished - Sep 7 2005

Keywords

  • Gastrointestinal stromal tumor
  • Gastrointestinal tract
  • Intra-abdominal fibromatosis

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor: A case report'. Together they form a unique fingerprint.

  • Cite this