Locally advanced cervical cancer complicating pregnancy: A case of competing risks from the Catholic University of the Sacred Heart in Rome

R De Vincenzo, L Tortorella, C Ricci, A F Cavaliere, G F Zannoni, M G Cefalo, G Scambia, A Fagotti

Research output: Contribution to journalArticle

Abstract

A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed with acute myelogenous leukemia. We highlight the pre-operative work-up, treatment options, safety, feasibility, and outcomes for the mother and her fetus.

Original languageEnglish
Pages (from-to)398-405
Number of pages8
JournalGynecologic Oncology
Volume150
Issue number3
DOIs
Publication statusPublished - Sep 2018

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Lymph Node Excision
Hysterectomy
Acute Myeloid Leukemia
Uterine Cervical Neoplasms
Fetus
Radiation
Safety
Drug Therapy
Pregnancy
Therapeutics

Keywords

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Squamous Cell/drug therapy
  • Cesarean Section
  • Chemotherapy, Adjuvant
  • Cisplatin/administration & dosage
  • Female
  • Humans
  • Hysterectomy
  • Infant, Newborn
  • Male
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Paclitaxel/administration & dosage
  • Pregnancy
  • Pregnancy Complications, Neoplastic/drug therapy
  • Salpingectomy
  • Uterine Cervical Neoplasms/drug therapy

Cite this

Locally advanced cervical cancer complicating pregnancy : A case of competing risks from the Catholic University of the Sacred Heart in Rome. / De Vincenzo, R; Tortorella, L; Ricci, C; Cavaliere, A F; Zannoni, G F; Cefalo, M G; Scambia, G; Fagotti, A.

In: Gynecologic Oncology, Vol. 150, No. 3, 09.2018, p. 398-405.

Research output: Contribution to journalArticle

De Vincenzo, R ; Tortorella, L ; Ricci, C ; Cavaliere, A F ; Zannoni, G F ; Cefalo, M G ; Scambia, G ; Fagotti, A. / Locally advanced cervical cancer complicating pregnancy : A case of competing risks from the Catholic University of the Sacred Heart in Rome. In: Gynecologic Oncology. 2018 ; Vol. 150, No. 3. pp. 398-405.
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