Locally advanced cervical cancer complicating pregnancy: A case of competing risks from the Catholic University of the Sacred Heart in Rome

R. De Vincenzo, L. Tortorella, C. Ricci, A.F. Cavaliere, G.F. Zannoni, M.G. Cefalo, G. Scambia, A. Fagotti

Research output: Contribution to journalArticle

Abstract

A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed with acute myelogenous leukemia. We highlight the pre-operative work-up, treatment options, safety, feasibility, and outcomes for the mother and her fetus. © 2018 Elsevier Inc.
Original languageEnglish
Pages (from-to)398-405
Number of pages8
JournalGynecologic Oncology
Volume150
Issue number3
DOIs
Publication statusPublished - 2018

Fingerprint

Lymph Node Excision
Hysterectomy
Acute Myeloid Leukemia
Uterine Cervical Neoplasms
Fetus
Radiation
Safety
Drug Therapy
Pregnancy
Therapeutics

Keywords

  • acute myeloid leukemia
  • adult
  • advanced cancer
  • Apgar score
  • Article
  • cancer patient
  • cancer staging
  • cancer survival
  • case report
  • cesarean section
  • chemoradiotherapy
  • chemosensitization
  • clinical article
  • external beam radiotherapy
  • female
  • gestational age
  • hospital admission
  • human
  • human tissue
  • immunohistochemistry
  • Italy
  • lymph node dissection
  • neoadjuvant chemotherapy
  • nuclear magnetic resonance imaging
  • nulligravida
  • outcome assessment
  • patient safety
  • pelvic examination
  • placenta previa
  • pregnancy
  • pregnancy complication
  • pregnancy outcome
  • pregnant woman
  • priority journal
  • radiation oncologist
  • radical hysterectomy
  • risk factor
  • solutio placentae
  • tumor volume
  • uterine cervix cancer
  • uterine cervix carcinoma
  • adjuvant chemotherapy
  • hysterectomy
  • male
  • neoadjuvant therapy
  • newborn
  • pathology
  • salpingectomy
  • squamous cell carcinoma
  • uterine cervix tumor, antineoplastic agent
  • cisplatin
  • paclitaxel, Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Squamous Cell
  • Cesarean Section
  • Chemotherapy, Adjuvant
  • Cisplatin
  • Female
  • Humans
  • Hysterectomy
  • Infant, Newborn
  • Male
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Paclitaxel
  • Pregnancy
  • Pregnancy Complications, Neoplastic
  • Salpingectomy
  • Uterine Cervical Neoplasms

Cite this

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title = "Locally advanced cervical cancer complicating pregnancy: A case of competing risks from the Catholic University of the Sacred Heart in Rome",
abstract = "A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed with acute myelogenous leukemia. We highlight the pre-operative work-up, treatment options, safety, feasibility, and outcomes for the mother and her fetus. {\circledC} 2018 Elsevier Inc.",
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author = "{De Vincenzo}, R. and L. Tortorella and C. Ricci and A.F. Cavaliere and G.F. Zannoni and M.G. Cefalo and G. Scambia and A. Fagotti",
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AU - Tortorella, L.

AU - Ricci, C.

AU - Cavaliere, A.F.

AU - Zannoni, G.F.

AU - Cefalo, M.G.

AU - Scambia, G.

AU - Fagotti, A.

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AB - A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed with acute myelogenous leukemia. We highlight the pre-operative work-up, treatment options, safety, feasibility, and outcomes for the mother and her fetus. © 2018 Elsevier Inc.

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KW - chemosensitization

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