Location of the Primary Tumor is Not an Independent Predictor of Cancer Specific Mortality in Patients With Upper Urinary Tract Urothelial Carcinoma

Hendrik Isbarn, Claudio Jeldres, Shahrokh F. Shariat, Daniel Liberman, Maxine Sun, Giovanni Lughezzani, Hugues Widmer, Philippe Arjane, Daniel Pharand, Margit Fisch, Markus Graefen, Francesco Montorsi, Paul Perrotte, Pierre I. Karakiewicz

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The prognostic significance of renal pelvis vs ureteral upper urinary tract urothelial carcinoma tumor location is controversial. We assessed the prognostic significance of upper urinary tract urothelial carcinoma tumor location in a large, population based data set. Materials and Methods: Our analyses relied on 2,824 patients treated with nephroureterectomy for upper urinary tract urothelial carcinoma within 9 SEER registries between 1988 and 2004. Univariable and multivariable models tested the effect of tumor location on cancer specific mortality rates. Covariates consisted of age, race, SEER registry, gender, type of surgery (nephroureterectomy with vs without bladder cuff removal), pT stage, pN stage, grade and year of surgery. Results: Relative to ureteral tumors renal pelvis tumors were of higher stage (T3/T4 disease 38.4% vs 57.9%, p

Original languageEnglish
Pages (from-to)2177-2181
Number of pages5
JournalJournal of Urology
Volume182
Issue number5
DOIs
Publication statusPublished - Nov 2009

Keywords

  • carcinoma
  • kidney pelvis
  • transitional cell
  • ureter
  • urinary tract

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

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