Locations of mouse DNA damage response and repair loci, and cancer risk modifiers

Robert A. Bulman, Tommaso A. Dragani, Simon D. Bouffler, Roger Cox

Research output: Contribution to journalArticlepeer-review

Abstract

An outline is presented of an electronically accessible database that compares the locations of mouse genes involved in DNA repair, apoptosis, cell cycle and signal transduction with those of known cancer risk modifier genes. The database has a primary but not exclusive focus on modifiers of ionizing radiation (IR) cancer risk and genes involved in IR-induced DNA damage responses. The database (http://www.hpa.org.uk/radiation/publications/ misc_publications/dna_database/dna_database.htm) provides a useful tool for assessing the role of DNA damage response genes in cancer predisposition. Crown

Original languageEnglish
Pages (from-to)274-277
Number of pages4
JournalDNA Repair
Volume5
Issue number2
DOIs
Publication statusPublished - Feb 3 2006

Keywords

  • Cancer
  • DNA repair
  • Ionizing radiation

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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