TY - JOUR
T1 - LombardIMA
T2 - A regional registry for coronary angioplasty in ST-elevation myocardial infarction
AU - Politi, Alessandro
AU - Martinoni, Alessandro
AU - Klugmann, Silvio
AU - Zanini, Roberto
AU - Onofri, Marco
AU - Guagliumi, Giulio
AU - Fiorentini, Cesare
AU - Lettieri, Corrado
AU - Belli, Guido
AU - Piccaluga, Emanuela
AU - De Cesare, Nicoletta
AU - D'Urbano, Maurizio
AU - Ettori, Federica
AU - Repetto, Alessandra
AU - Musumeci, Giuseppe
AU - Castiglioni, Battistina
AU - Colombo, Paola
AU - Passamonti, Enrico
AU - Bramucci, Ezio
AU - Cattaneo, Laura
AU - Ferrari, Giovanni
AU - Repetto, Sergio
AU - Bartorelli, Antonio
AU - Pirelli, Salvatore
AU - De Servi, Stefano
PY - 2011/1
Y1 - 2011/1
N2 - Background: Percutaneous coronary intervention (PCI) has been shown to be the best reperfusion therapy for acute myocardial infarction with ST-elevation (STEMI), but data from registries show differences in patient populations and outcomes between randomized trials and real life. Objectives: We sought to provide information about the current status of this treatment with a registry collecting data in Lombardy, the most densely populated region in Italy, with widespread availability of cathlabs and a well-established network for the treatment of STEMI. Methods and results: Patient enrolment was performed by 32 hub centres recruiting 3901 STEMI patients who underwent PCI procedures within 12 h of the onset of symptoms, of whom 3317 patients underwent primary PCI, 376 'facilitated' PCI, and 208 rescue PCI in cathlabs located, in 77% of cases, in the same hospital of admission. Inhospital and 30-day total death were 4.4 and 6.6%, respectively. At multivariate analysis independent negative predictors of 30-day mortality were Killip class 3-4, number of involved ECG leads, chronic renal failure and age, whereas positive predictors were ST resolution more than 50% and postprocedural grade 3 thrombolysis in myocardial infarction flow. Conclusions: LombardIMA PCI registry enrolled STEMI patients representing a real-world population treated with PCI. Findings presented in this study may provide a benchmark for similar registries undertaken in other Italian regions and may be helpful to assess future possible developments of care for STEMI patients.
AB - Background: Percutaneous coronary intervention (PCI) has been shown to be the best reperfusion therapy for acute myocardial infarction with ST-elevation (STEMI), but data from registries show differences in patient populations and outcomes between randomized trials and real life. Objectives: We sought to provide information about the current status of this treatment with a registry collecting data in Lombardy, the most densely populated region in Italy, with widespread availability of cathlabs and a well-established network for the treatment of STEMI. Methods and results: Patient enrolment was performed by 32 hub centres recruiting 3901 STEMI patients who underwent PCI procedures within 12 h of the onset of symptoms, of whom 3317 patients underwent primary PCI, 376 'facilitated' PCI, and 208 rescue PCI in cathlabs located, in 77% of cases, in the same hospital of admission. Inhospital and 30-day total death were 4.4 and 6.6%, respectively. At multivariate analysis independent negative predictors of 30-day mortality were Killip class 3-4, number of involved ECG leads, chronic renal failure and age, whereas positive predictors were ST resolution more than 50% and postprocedural grade 3 thrombolysis in myocardial infarction flow. Conclusions: LombardIMA PCI registry enrolled STEMI patients representing a real-world population treated with PCI. Findings presented in this study may provide a benchmark for similar registries undertaken in other Italian regions and may be helpful to assess future possible developments of care for STEMI patients.
KW - Acute coronary syndromes
KW - Acute myocardial infarction
KW - Primary angioplasty
KW - Registries
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U2 - 10.2459/JCM.0b013e328340334d
DO - 10.2459/JCM.0b013e328340334d
M3 - Article
C2 - 20935576
AN - SCOPUS:79953726715
VL - 12
SP - 43
EP - 50
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 1
ER -