Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development

B. Koletzko, C. Agostoni, S. E. Carlson, T. Clandinin, G. Hornstra, M. Neuringer, R. Uauy, Y. Yamashiro, P. Willatts

Research output: Contribution to journalArticle

206 Citations (Scopus)

Abstract

This paper reports on the conclusions of a workshop on the role of long chain polyunsaturated fatty acids (LC-PUFA) in maternal and child health. The attending investigators involved in the majority of randomized trials examining LC-PUFA status and functional outcomes summarize the current knowledge in the field and make recommendations for dietary practice. Only studies published in full or in abstract form were used as our working knowledge base. Conclusions: For healthy infants we recommend and strongly support breastfeeding as the preferred method of feeding, which supplies preformed LC-PUFA. Infant formulas for term infants should contain at least 0.2% of total fatty acids as docosahexaenoic acid (DHA) and 0.35% as arachidonic acid (AA). Since preterm infants are born with much less total body DHA and AA, we suggest that preterm infant formulas should include at least 0.35% DHA and 0.4% AA. Higher levels might confer additional benefits and should be further investigated because optimal dietary intakes for term and preterm infants remain to be defined. For pregnant and lactating women we consider it premature to recommend specific LC-PUFA intakes. However, it seems prudent for pregnant and lactating women to include some food sources of DHA in their diet in view of their assumed increase in LC-PUFA demand and the relationship between maternal and foetal DHA status.

Original languageEnglish
Pages (from-to)460-464
Number of pages5
JournalActa Paediatrica, International Journal of Paediatrics
Volume90
Issue number4
Publication statusPublished - 2001

Fingerprint

Docosahexaenoic Acids
Unsaturated Fatty Acids
Arachidonic Acid
Premature Infants
Infant Formula
Pregnant Women
Feeding Methods
Knowledge Bases
Breast Feeding
Fatty Acids
Mothers
Research Personnel
Diet
Education
Food

Keywords

  • Arachidonic acid
  • Dietary requirements
  • Docosahexaenoic acid
  • Essential fatty acids
  • Infant nutrition

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Koletzko, B., Agostoni, C., Carlson, S. E., Clandinin, T., Hornstra, G., Neuringer, M., ... Willatts, P. (2001). Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. Acta Paediatrica, International Journal of Paediatrics, 90(4), 460-464.

Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. / Koletzko, B.; Agostoni, C.; Carlson, S. E.; Clandinin, T.; Hornstra, G.; Neuringer, M.; Uauy, R.; Yamashiro, Y.; Willatts, P.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 90, No. 4, 2001, p. 460-464.

Research output: Contribution to journalArticle

Koletzko, B, Agostoni, C, Carlson, SE, Clandinin, T, Hornstra, G, Neuringer, M, Uauy, R, Yamashiro, Y & Willatts, P 2001, 'Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development', Acta Paediatrica, International Journal of Paediatrics, vol. 90, no. 4, pp. 460-464.
Koletzko, B. ; Agostoni, C. ; Carlson, S. E. ; Clandinin, T. ; Hornstra, G. ; Neuringer, M. ; Uauy, R. ; Yamashiro, Y. ; Willatts, P. / Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. In: Acta Paediatrica, International Journal of Paediatrics. 2001 ; Vol. 90, No. 4. pp. 460-464.
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