Long-lasting CD3+ T-cell deficiency after cord blood stem cell transplantation in a human herpesvirus 6-infected child

Manola Comar, Pierlanfranco D'Agaro, Douglas Horejsh, Monica Galvan, Simona Fiorentini, Marino Andolina, Arnaldo Caruso, Dario Di Luca, Cesare Campello

Research output: Contribution to journalArticlepeer-review

Abstract

We report a long-lasting (8-month) reactivation of human herpesvirus 6 (HHV-6) infection in child who had undergone cord blood stem cell transplantation. The reactivation was characterized by high viral loads and by immediate-early mRNA positivity. HHV-6 infection was associated with a deep depletion of CD3, while the CD4/CD8 ratio remained substantially unchanged.

Original languageEnglish
Pages (from-to)2002-2003
Number of pages2
JournalJournal of Clinical Microbiology
Volume43
Issue number4
DOIs
Publication statusPublished - Apr 2005

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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