Abstract
Setting: Obesity surgery has been proposed as a treatment option for diabetic patients with body mass index (BMI)2, but the efficacy of metabolic surgery has not been conclusively determined. Objective: To evaluate the long-term metabolic outcome of non-morbidly obese (NMO) patients with type 2 diabetes (T2D) after biliopancreatic diversion (BPD). Material and methods: Two groups of T2D patients with different degree of obesity (NMO, 17 cases, BMI 25-35 kg/m2; and morbidly obese [MO], 13 cases, BMI>35 kg/m2) were studied before and at 1 and 5 years after BPD in a university hospital setting. Insulin secretion was assessed by acute insulin response (AIR) to intravenous glucose and by insulinogenic index (IGI). Results: In all MO patients, T2D was remitted or controlled (1 case) at 1 year and results were maintained at 5 years; AIR (μU/mL) and IGI (μU/mg) improved (P
| Original language | English |
|---|---|
| Journal | Surgery for Obesity and Related Diseases |
| DOIs | |
| Publication status | Accepted/In press - Aug 25 2015 |
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Keywords
- Acute insulin response
- Bariatric surgery
- Biliopancreatic diversion
- Insulinogenic index
- Obesity degree
- Type 2 diabetes
ASJC Scopus subject areas
- Surgery
Cite this
Long-term clinical and functional impact of biliopancreatic diversion on type 2 diabetes in morbidly and non-morbidly obese patients. / Scopinaro, Nicola; Camerini, Giovanni; Papadia, Francesco; Andraghetti, Gabriella; Cordera, Renzo; Adami, Gian Franco.
In: Surgery for Obesity and Related Diseases, 25.08.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term clinical and functional impact of biliopancreatic diversion on type 2 diabetes in morbidly and non-morbidly obese patients
AU - Scopinaro, Nicola
AU - Camerini, Giovanni
AU - Papadia, Francesco
AU - Andraghetti, Gabriella
AU - Cordera, Renzo
AU - Adami, Gian Franco
PY - 2015/8/25
Y1 - 2015/8/25
N2 - Setting: Obesity surgery has been proposed as a treatment option for diabetic patients with body mass index (BMI)2, but the efficacy of metabolic surgery has not been conclusively determined. Objective: To evaluate the long-term metabolic outcome of non-morbidly obese (NMO) patients with type 2 diabetes (T2D) after biliopancreatic diversion (BPD). Material and methods: Two groups of T2D patients with different degree of obesity (NMO, 17 cases, BMI 25-35 kg/m2; and morbidly obese [MO], 13 cases, BMI>35 kg/m2) were studied before and at 1 and 5 years after BPD in a university hospital setting. Insulin secretion was assessed by acute insulin response (AIR) to intravenous glucose and by insulinogenic index (IGI). Results: In all MO patients, T2D was remitted or controlled (1 case) at 1 year and results were maintained at 5 years; AIR (μU/mL) and IGI (μU/mg) improved (P
AB - Setting: Obesity surgery has been proposed as a treatment option for diabetic patients with body mass index (BMI)2, but the efficacy of metabolic surgery has not been conclusively determined. Objective: To evaluate the long-term metabolic outcome of non-morbidly obese (NMO) patients with type 2 diabetes (T2D) after biliopancreatic diversion (BPD). Material and methods: Two groups of T2D patients with different degree of obesity (NMO, 17 cases, BMI 25-35 kg/m2; and morbidly obese [MO], 13 cases, BMI>35 kg/m2) were studied before and at 1 and 5 years after BPD in a university hospital setting. Insulin secretion was assessed by acute insulin response (AIR) to intravenous glucose and by insulinogenic index (IGI). Results: In all MO patients, T2D was remitted or controlled (1 case) at 1 year and results were maintained at 5 years; AIR (μU/mL) and IGI (μU/mg) improved (P
KW - Acute insulin response
KW - Bariatric surgery
KW - Biliopancreatic diversion
KW - Insulinogenic index
KW - Obesity degree
KW - Type 2 diabetes
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UR - http://www.scopus.com/inward/citedby.url?scp=84959285375&partnerID=8YFLogxK
U2 - 10.1016/j.soard.2015.12.011
DO - 10.1016/j.soard.2015.12.011
M3 - Article
AN - SCOPUS:84959285375
JO - Surgery for Obesity and Related Diseases
JF - Surgery for Obesity and Related Diseases
SN - 1550-7289
ER -