Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data

J. Sastre-Garriga, G. T. Ingle, M. Rovaris, N. Téllez, B. Jasperse, D. R. Altmann, B. Benedetti, V. L. Stevenson, M. Cercignani, S. M. Leary, F. Barkhof, B. Brochet, V. Dousset, M. Filippi, X. Montalban, N. F. Kalkers, C. H. Polman, A. Rovira, D. H. Miller, Alan J. Thompson

Research output: Contribution to journalArticlepeer-review

Abstract

The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.

Original languageEnglish
Pages (from-to)633-635
Number of pages3
JournalNeurology
Volume65
Issue number4
DOIs
Publication statusPublished - Aug 23 2005

ASJC Scopus subject areas

  • Neuroscience(all)

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