Long term complete remission of severe nephrotic syndrome secondary to diffuse global (IV-G) lupus nephritis following autologous, haematopoietic peripheral stem (CD34+) cell transplantation

A. M. Marmont, F. Gualandi, M. T. Van Lint, C. Guastoni, A. Bacigalupo

Research output: Contribution to journalArticle

Abstract

Autologous haematopoietic stem cell transplantation has become an accepted powerful therapeutic procedure for patients with severe, intractable SLE. Here we describe a 26-year old patient with stage IV-G diffuse global proliferative lupus nephritis and refractory nephrotic syndrome who responded to autologous peripheral stem cell transplantation (ASCT) after two mobilization procedures. Five years later the patient is in complete clinical and immunologie remission. The indications for ASCT and its mechanism of action are briefly discussed.

Original languageEnglish
Pages (from-to)44-46
Number of pages3
JournalLupus
Volume15
Issue number1
DOIs
Publication statusPublished - 2006

Keywords

  • Autologous stem cell transplantation
  • Lupus nephritis
  • Nephrotic syndrome

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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